ANTIMICROBIAL AND ANTIBIOFILM ACTIVITIES OF VARIOUS VEGETABLE OILS AGAINST HELICOBACTER PYLORI

Objective: Vegetable oils have various biologically active components, including antibacterial, antioxidant, and anti-inflammatory properties. These oils help control nausea, vomiting, coughing and gas, as well as diarrhea and dyspepsia. It also helps to reduce stomach bloating and intestinal spasm pain. To sum up, the objective of this investigation was to assess the antibacterial and antibiofilm properties of twelve different vegetable oils against the reference strain of Helicobacter pylori, NTCC 11637. Material and Method: For antibacterial activity, the minimum inhibitory concentration and the agar-well diffusion method were employed, and for antibiofilm activity, the microplate method. Result and Discussion: Vegetable oils showed antimicrobial activity at concentrations of 62.5-15.625 μg/ml and antibiofilm activity at concentrations of 250-15.625 μg/ml. According to our findings, the vegetable oils we utilized may have the ability to form a novel class of Helicobacter pylori inhibitors with anti-H. pylori properties.