一名接受静脉类固醇治疗的非动脉炎性后部缺血性视神经病变患者的视野改善情况

Shinji Makino
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摘要

一名 50 岁的男子因左眼鼻腔视野缺损前来就诊。他的病史并无异常。经眼科检查,他双眼的最佳矫正视力(BCVA)均为 1.2。眼底镜检查未发现异常。戈德曼视野测试显示左眼有鼻腔视野缺损。患者被诊断为左眼 NPION,并在未接受治疗的情况下接受了随访。然而,初诊四天后,他的左眼 BCVA 下降到数指。戈德曼视野测试显示其鼻腔视野完全缺损,并伴有中央绝对性散光。入院后,患者接受了为期 3 天的甲基强的松龙脉冲静脉注射治疗。三个月后,他的左眼视力改善至 0.8,但仍存在中心相对性视网膜障。六个月后,他的 BCVA 保持在 0.8,中心相对性视网膜瘤消失。然而,左眼的视盘看起来弥漫性苍白。本病例表明,类固醇疗法是后部缺血性视神经病变重症患者的一种选择。
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Visual Field Improvement in Non-Arteritic Posterior Ischemic Optic Neuropathy in a Patient Treated with Intravenous Steroids
A 50-year-old man presented with a nasal visual field defect in the left eye. His medical history was unremarkable. On ophthalmic examination, his best-corrected visual acuity (BCVA) was 1.2 in both eyes. Fundoscopy revealed no abnormalities in either eye. Goldmann visual field test showed a nasal visual field defect in the left eye. The patient was diagnosed with NPION of the left eye and was followed up without treatment. However, four days after the initial visit, his BCVA decreased to counting finger in the left eye. Goldmann visual field test showed a complete nasal visual field defect with central absolute scotoma. Following admission, the patient was treated for 3 days with intravenous methylprednisolone pulse therapy. Three months later, his BCVA was improved to 0.8 in the left eye, but central relative scotoma was remained. Six months later, his BCVA was maintained at 0.8, and central relative scotoma was disappeared. However, the optic disc looked diffusely pale in the left eye. This case highlights that steroid therapy is an option for severe cases with posterior ischemic optic neuropathy.
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