小细胞肺癌中纤维的中间表达与体外数据相关性较差。

European journal of respiratory diseases. Supplement Pub Date : 1987-01-01

H H Berendsen, L de Ley, S Poppema, P E Postmus, H J Sluiter, T H The

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摘要

一组单克隆抗体，用于检测不同的中等大小的纤维蛋白，前瞻性地应用于1985年就诊于我们诊所的所有scclc患者的标本。抗体的反应性随后与临床数据相关。结果表明，一个异质模式的反应性评估抗体。然而，这种异质性并不是SCLC细胞系中中等大小丝表达的直接延伸。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Intermediate filament expression in small cell lung cancer; poor correlation to in vitro data.

A panel of monoclonal antibodies, detecting different intermediate sized filament proteins, was prospectively applied on all specimens derived from S.C.L.C. patients attending our clinic in 1985. Reactivity with the antibodies was subsequently correlated to clinical data. The results indicate a heterogeneous pattern of reactivity of the assessed antibodies. However this heterogeneity is not a straightforward extension of the intermediate sized filament expression in SCLC cell lines.

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European journal of respiratory diseases. Supplement

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Small cell lung cancer. Small cell lung cancer. Monoclonal antibodies in lung cancer pathology. The rôle of proteases and antiproteases in bronchial secretions. Adverse effects of toxins and drugs on the surfactant systems.