{"title":"十二指肠神经内分泌瘤治疗后[177 Lu]Lu-DOTATATE闪烁扫描意外显示胆囊，模仿肝转移灶","authors":"Parth Baberwal, R. Parghane, Sandip Basu","doi":"10.1055/s-0044-1788073","DOIUrl":null,"url":null,"abstract":"Abstract We present a rare case of physiological uptake of [ 177 Lu]Lu-DOTATATE in the gallbladder, observed post-therapy, in a 47-year-old man with grade I duodenal neuroendocrine tumor (NET), despite no uptake being observed pre-therapy in the somatostatin receptor-positron emission tomography. On planar scintigraphy, the gallbladder uptake could have been misidentified as liver metastasis. By utilizing single photon emission computed tomography/computed tomography imaging, we were able to precisely localize the tracer and obtain anatomical morphological characteristics, thereby averting the potential for misinterpretation of liver metastasis resulting from the gallbladder's physiological uptake of [ 177 Lu]Lu-DOTATATE in NET patients.","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Incidental Visualization of Gallbladder on Post-therapy [ 177 Lu]Lu-DOTATATE Scintigraphy Mimicking a Liver Metastasis in a Duodenal Neuroendocrine Tumor\",\"authors\":\"Parth Baberwal, R. Parghane, Sandip Basu\",\"doi\":\"10.1055/s-0044-1788073\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract We present a rare case of physiological uptake of [ 177 Lu]Lu-DOTATATE in the gallbladder, observed post-therapy, in a 47-year-old man with grade I duodenal neuroendocrine tumor (NET), despite no uptake being observed pre-therapy in the somatostatin receptor-positron emission tomography. On planar scintigraphy, the gallbladder uptake could have been misidentified as liver metastasis. By utilizing single photon emission computed tomography/computed tomography imaging, we were able to precisely localize the tracer and obtain anatomical morphological characteristics, thereby averting the potential for misinterpretation of liver metastasis resulting from the gallbladder's physiological uptake of [ 177 Lu]Lu-DOTATATE in NET patients.\",\"PeriodicalId\":23742,\"journal\":{\"name\":\"World Journal of Nuclear Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2024-07-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World Journal of Nuclear Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0044-1788073\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Nuclear Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0044-1788073","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
摘要
摘要 我们报告了一例罕见的胆囊生理性摄取[177 Lu]Lu-DOTATATE 的病例，该患者 47 岁，患有 I 级十二指肠神经内分泌肿瘤（NET），尽管在治疗前的体生长抑素受体正电子发射断层扫描中未观察到摄取，但在治疗后观察到了胆囊摄取。在平面闪烁扫描中，胆囊摄取可能被误认为是肝转移。通过利用单光子发射计算机断层扫描/计算机断层扫描成像，我们能够精确定位示踪剂并获得解剖形态学特征，从而避免了因NET患者胆囊对[177 Lu]Lu-DOTATATE 的生理性摄取而误诊为肝转移的可能性。
Incidental Visualization of Gallbladder on Post-therapy [ 177 Lu]Lu-DOTATATE Scintigraphy Mimicking a Liver Metastasis in a Duodenal Neuroendocrine Tumor
Abstract We present a rare case of physiological uptake of [ 177 Lu]Lu-DOTATATE in the gallbladder, observed post-therapy, in a 47-year-old man with grade I duodenal neuroendocrine tumor (NET), despite no uptake being observed pre-therapy in the somatostatin receptor-positron emission tomography. On planar scintigraphy, the gallbladder uptake could have been misidentified as liver metastasis. By utilizing single photon emission computed tomography/computed tomography imaging, we were able to precisely localize the tracer and obtain anatomical morphological characteristics, thereby averting the potential for misinterpretation of liver metastasis resulting from the gallbladder's physiological uptake of [ 177 Lu]Lu-DOTATATE in NET patients.
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