微胶囊可可多酚对偏心运动后大血管和微血管功能的影响

Gustavo Vieira de Oliveira, Leonardo Victor Miranda de Souza, Olavo João Frederico Ramos Junior, Mônica Volino-Souza, T. Alvares
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引用次数: 0

摘要

背景:有证据表明,非惯性运动(如偏心运动)会增加活性氧,诱发内皮功能障碍,而内皮功能障碍在心血管疾病的发展中起着核心作用。可可等富含多酚的食物因其抗氧化作用而被广泛研究其对血管功能的影响。目的:本研究旨在评估微胶囊可可(MC)多酚对偏心运动后血流介导的扩张(FMD)反应和前臂肌肉氧合(StO2)参数的影响。研究方法13 名身体活跃的成年人参加了一项随机、双盲和交叉研究。在进行偏心运动和补充 MC 或安慰剂 24 小时、48 小时和 72 小时前后,对 FMD 和 StO2 进行了评估。结果显示服用 MC 和安慰剂后,FMD 反应和 StO2 参数无明显差异(P > 0.05)。结论单剂量 MC 不会改变健康人偏心运动后的 FMD 和肌肉 StO2 参数。
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Effect of Microencapsulated Cocoa Polyphenols on Macro- and Microvascular Function after Eccentric Exercise
Background: Evidence has demonstrated that non-habitual exercise, such as eccentric exercise, can increase reactive oxygen species and induce endothelial dysfunction, which plays a central role in the development of cardiovascular disease. Polyphenol-rich foods, such as cocoa, have been widely investigated in vascular function due to their antioxidant effect. Aims: The goal of this study was to evaluate the impact of microencapsulated cocoa (MC) polyphenols in the flow-mediated dilation (FMD) response and forearm muscle oxygenation (StO2) parameters after an eccentric exercise. Methods: Thirteen physically active adults were enrolled in a randomized, double-blind, and crossover study. FMD and StO2 were evaluated before and after 24 h, 48 h, and 72 h of eccentric exercise and MC or placebo supplementation. Results: No significant difference in FMD response and StO2 parameters was observed after MC and placebo (p > 0.05). Conclusions: A single dose of MC did not change FMD and muscle StO2 parameters after eccentric exercise in healthy individuals.
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