"儿童下呼吸道感染不同治疗方法的疗效 "数据库简介

Yu Deng, Bing Hu, Yi Zou, Zhengxiu Luo, Guang-li Zhang, Jinhai Ma, Changshan Liu, Xiaoyan Dong, Huifen Zi, Chuangli Hao, Rongjun Lin, Xiangrong Zheng, Bingfei Li, Fenhua Chen, Mei Fang, Weimin Tian, Zhiqiang Zhuo, Deyu Zhao, Zhimin Chen, Yuejie Zheng, Jingyang Zheng, Yong Yin, Qiuyu Tang, Liqun Wu, Li Gu, Jinzhun Wu, Liyi He, T. Ai, Ning Wang, Minjun Zhang, Hailin Zhang, Hanmin Liu, Youxiang Zhang, Jianguo Hong, Zhiying Han, Yunbo Mo, Hongmei Qiao, Zhiliang Tian, Zengni Li, Q. Lu, Enmei Liu
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摘要

本研究旨在建立中国儿童下呼吸道感染(LRTI)不同治疗方式的登记数据库,从而填补中国儿童下呼吸道感染临床特点、治疗方式和合理用药方面的知识空白,提供大量连续、完整、科学、客观的临床数据和信息交流平台。多中心收集、汇总这些儿童的临床就诊数据,并利用医学信息学和统计学技术对其进行分析,以挖掘其潜在价值。初步建立了数据库,并根据该数据库中登记的 4805 名患者构建了真实世界研究队列。肺炎是最常见的 LRTIs 类型(72.44%),其次是急性支气管炎(20.71%)。登记的 LRTI 儿童的平均年龄为 3.26±2.84 岁,男孩占样本的 59.21%。在登记的儿童中,肺炎和急性支气管炎在 1-3 岁儿童(27.44%)和 3-6 岁儿童(34.16%)中的发病率最高。这个全国性、多中心、儿童 LRTIs 观察数据库阐明了中国儿童 LRTIs 的真实世界特征和治疗模式。该数据库将有助于提高临床医生的研究效率,促进在真实世界的医疗大数据中探索潜在的临床模式。
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Introduction to the database “efficacy of different treatment modalities for lower respiratory tract infections in children”
This study aimed to establish a registry database of different treatment modalities for lower respiratory tract infections (LRTIs) in Chinese children, thereby filling gaps in knowledge on clinical characteristics, treatment modalities, and rational drug use in relation to LRTIs in Chinese children, and providing large amounts of continuous, complete, scientific, and objective clinical data, and an information exchange platform. Multicenter data from these children's clinical visits were collected, pooled, and analyzed using medical informatics and statistical techniques to explore their potential value. The database was preliminarily established and a real‐world study cohort was constructed based on a total of 4805 patients registered in this database. Pneumonia was identified as the most common type of LRTIs (72.44%), followed by acute bronchitis (20.71%). The mean age of the enrolled children with LRTIs was 3.26 ± 2.84 years, and boys accounted for 59.21% of the samples. Among the enrolled children, pneumonia and acute bronchitis had the highest incidence in children aged 1–3 years (27.44%) and those aged 3–6 years (34.16%), respectively. In this national, multicenter, observational database of LRTIs in children, the real‐world characteristics and treatment modalities for LRTIs in Chinese children are elucidated. This database will help improve the research efficiency of clinicians and facilitate the exploration of underlying clinical patterns in real‐world medical big data.
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