David E Ruckle, Alexander Chang, J. Jesurajan, Bradley Carlson, Matthew T. Gulbrandsen, R. Rice, M. D. Wongworawat
{"title":"吸食大麻会增加骨科手术后手术部位感染的几率吗?一项回顾性队列研究","authors":"David E Ruckle, Alexander Chang, J. Jesurajan, Bradley Carlson, Matthew T. Gulbrandsen, R. Rice, M. D. Wongworawat","doi":"10.1097/bot.0000000000002866","DOIUrl":null,"url":null,"abstract":"\n \n Does marijuana smoking increase the risk of surgical site infection (SSI) after open reduction and internal fixation of fractures?\n \n \n \n \n \n \n Retrospective\n \n \n \n Single academic level 1 trauma center in Southern California\n \n \n \n Adult patients who underwent open treatment for closed fractures between January 2009 and December 2021, had hardware placed, and had at least 6 months of postoperative follow up.\n \n \n \n Risk factors associated with the development of SSI were compared between current inhalational marijuana users and non-marijuana users.\n \n \n \n Complete data was available on 4,802 patients after exclusion of 82 who did not have a complete variable set. At the time of surgery 24% (1,133 patients) were current users of marijuana. At final follow up (minimum 6 months), there was a 1.6% infection rate (75 patients). The average age of the infection free group was 46.1 ± 23.1 and the average age of the SSI group was 47.0 ± 20.3 (p=0.73). 2,703 (57%) in the infection free group were male compared to 48 (64%) in the SSI group (p=0.49). On multivariate analysis, longer operative times (OR 1.002 [95% CI: 1.001-1.004]), diabetic status (OR 2.084 [95% CI: 1.225-3.547]), and current tobacco use (OR 2.493 [95% CI: 1.514-4.106]) (p<0.01 for all) were associated with an increased risk of SSI; however, current marijuana use was not (OR 0.678 [95% CI: 0.228-2.013], p=0.48).\n \n \n \n Tobacco use, diabetes, and longer operative times were associated with the development of SSI after open reduction and internal fixation of fractures; however, marijuana smoking was not shown to be associated with the development of SSI.\n \n \n \n Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.\n","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Does Marijuana Smoking Increase the Odds of Surgical Site Infection after Orthopaedic Surgery? A Retrospective Cohort Study\",\"authors\":\"David E Ruckle, Alexander Chang, J. Jesurajan, Bradley Carlson, Matthew T. Gulbrandsen, R. Rice, M. D. Wongworawat\",\"doi\":\"10.1097/bot.0000000000002866\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n \\n Does marijuana smoking increase the risk of surgical site infection (SSI) after open reduction and internal fixation of fractures?\\n \\n \\n \\n \\n \\n \\n Retrospective\\n \\n \\n \\n Single academic level 1 trauma center in Southern California\\n \\n \\n \\n Adult patients who underwent open treatment for closed fractures between January 2009 and December 2021, had hardware placed, and had at least 6 months of postoperative follow up.\\n \\n \\n \\n Risk factors associated with the development of SSI were compared between current inhalational marijuana users and non-marijuana users.\\n \\n \\n \\n Complete data was available on 4,802 patients after exclusion of 82 who did not have a complete variable set. At the time of surgery 24% (1,133 patients) were current users of marijuana. At final follow up (minimum 6 months), there was a 1.6% infection rate (75 patients). The average age of the infection free group was 46.1 ± 23.1 and the average age of the SSI group was 47.0 ± 20.3 (p=0.73). 2,703 (57%) in the infection free group were male compared to 48 (64%) in the SSI group (p=0.49). On multivariate analysis, longer operative times (OR 1.002 [95% CI: 1.001-1.004]), diabetic status (OR 2.084 [95% CI: 1.225-3.547]), and current tobacco use (OR 2.493 [95% CI: 1.514-4.106]) (p<0.01 for all) were associated with an increased risk of SSI; however, current marijuana use was not (OR 0.678 [95% CI: 0.228-2.013], p=0.48).\\n \\n \\n \\n Tobacco use, diabetes, and longer operative times were associated with the development of SSI after open reduction and internal fixation of fractures; however, marijuana smoking was not shown to be associated with the development of SSI.\\n \\n \\n \\n Prognostic Level III. 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Does Marijuana Smoking Increase the Odds of Surgical Site Infection after Orthopaedic Surgery? A Retrospective Cohort Study
Does marijuana smoking increase the risk of surgical site infection (SSI) after open reduction and internal fixation of fractures?
Retrospective
Single academic level 1 trauma center in Southern California
Adult patients who underwent open treatment for closed fractures between January 2009 and December 2021, had hardware placed, and had at least 6 months of postoperative follow up.
Risk factors associated with the development of SSI were compared between current inhalational marijuana users and non-marijuana users.
Complete data was available on 4,802 patients after exclusion of 82 who did not have a complete variable set. At the time of surgery 24% (1,133 patients) were current users of marijuana. At final follow up (minimum 6 months), there was a 1.6% infection rate (75 patients). The average age of the infection free group was 46.1 ± 23.1 and the average age of the SSI group was 47.0 ± 20.3 (p=0.73). 2,703 (57%) in the infection free group were male compared to 48 (64%) in the SSI group (p=0.49). On multivariate analysis, longer operative times (OR 1.002 [95% CI: 1.001-1.004]), diabetic status (OR 2.084 [95% CI: 1.225-3.547]), and current tobacco use (OR 2.493 [95% CI: 1.514-4.106]) (p<0.01 for all) were associated with an increased risk of SSI; however, current marijuana use was not (OR 0.678 [95% CI: 0.228-2.013], p=0.48).
Tobacco use, diabetes, and longer operative times were associated with the development of SSI after open reduction and internal fixation of fractures; however, marijuana smoking was not shown to be associated with the development of SSI.
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
期刊介绍:
Journal of Orthopaedic Trauma is devoted exclusively to the diagnosis and management of hard and soft tissue trauma, including injuries to bone, muscle, ligament, and tendons, as well as spinal cord injuries. Under the guidance of a distinguished international board of editors, the journal provides the most current information on diagnostic techniques, new and improved surgical instruments and procedures, surgical implants and prosthetic devices, bioplastics and biometals; and physical therapy and rehabilitation.