比较急性胰腺炎的预后评分系统:急性胰腺炎床旁严重程度指数、WL 和中国简易评分系统评分

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-07-01 DOI:10.4103/tjem.tjem_14_24
Yunus Emre Güzel, Nese Çolak, Ahmet Can Okuv, Sefer Teymuroğlu, Muhammet İkbal Teke
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引用次数: 0

摘要

有几种评分系统被用于预测急性胰腺炎(AP)的预后,但它们的预测成功率各不相同。本研究比较了常用的急性胰腺炎床旁严重程度指数(BISAP)评分与新开发的WL评分和中国简易评分系统(CSSS)评分在预测急性胰腺炎患者死亡率和不良预后方面的有效性。 这项回顾性描述性研究纳入了2019年6月2日至2022年6月2日期间急诊科收治的所有AP患者。研究记录了患者的人口统计学特征、生命体征、实验室值和影像学检查结果,并计算了WL、CSSS和BISAP评分。比较了这些评分在预测不良后果和死亡率方面的有效性。 在 357 名患者中,53.2% 为男性,中位年龄为 62 岁(四分位间范围:48-75 岁)。在 7 天预后方面,WL 的曲线下面积 (AUC) 值为 0.956,CSSS 为 0.759,BISAP 为 0.871;在 30 天预后方面,WL 的曲线下面积 (AUC) 值为 0.941,CSSS 为 0.823,BISAP 为 0.901;在不良预后方面,WL 的曲线下面积 (AUC) 值为 0.792,CSSS 为 0.769,BISAP 为 0.731。 在 AP 患者中,WL、CSSS 和 BISAP 评分可有效预测不良预后和死亡率。在预测 7 天和 30 天死亡率及不良预后方面,WL 评分优于 CSSS 和 BISAP 评分。在预测死亡率方面,BISAP 是仅次于 WL 的系统。在预测不良预后方面,CSSS 是仅次于 WL 的第二好的系统。基于四项实验室参数计算 WL 评分的简便性使其成为首选。
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Comparing prognostic scoring systems in acute pancreatitis: Bedside Index of Severity in Acute Pancreatitis, WL, and Chinese Simple Scoring System Scores
Several scoring systems are used to predict prognosis in acute pancreatitis (AP), but their predictive success varies. This study compares the validity of the commonly used Bedside Index of Severity in AP (BISAP) score with the newly developed WL score and the Chinese Simple Scoring System (CSSS) score in predicting mortality and unfavorable prognostic outcomes in AP patients. This retrospective descriptive study included all AP patients presenting to the emergency department from June 2, 2019, to June 2, 2022. Patient demographics, vital signs, laboratory values, and imaging findings were recorded, and WL, CSSS, and BISAP scores were calculated. The effectiveness of these scores in predicting adverse outcomes and mortality was compared. Among 357 patients, 53.2% were male, with a median age of 62 years (interquartile range: 48–75). Area under the curve (AUC) values for 7-day outcomes were 0.956 for WL, 0.759 for CSSS, and 0.871 for BISAP; for 30-day outcomes, AUC values were 0.941 for WL, 0.823 for CSSS, and 0.901 for BISAP; and for poor prognostic outcomes, AUC values were 0.792 for WL, 0.769 for CSSS, and 0.731 for BISAP. In AP patients, WL, CSSS, and BISAP scores are effective predictors of unfavorable prognosis and mortality. WL score outperforms the CSSS and BISAP scores in predicting 7-day and 30-day mortality and poor prognosis. After WL, BISAP is the second-best system for predicting mortality. For predicting unfavorable prognoses, CSSS is the second-best system after WL. The simplicity of calculating the WL score based on four laboratory parameters makes it a preferable choice.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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