{"title":"肛门腺癌患者会阴疼痛的神经节假体阻滞和神经切除术:病例报告","authors":"Asmaranto Asmaranto, Dedi Susila","doi":"10.5530/pj.2024.16.120","DOIUrl":null,"url":null,"abstract":"sides and the posterior vagina/labia minora. The patient was diagnosed with adenomakarsinoma anus and underwent 25 sessions of chemotherapy. Despite taking analgesics such as oral morphine, tramadol, codeine, and paracetamol, the patient's pain persisted with a score of 7-8 on the NRS (Numeric Rating Scale). The patient was scheduled for a ganglion impar block using a neurolytic agent ABSTRACT Background : Anal adenocarcinoma is a rare malignancy with symptoms including tenesmus, rectal bleeding, and pain during defecation. The pain can significantly reduce a patient's quality of life and there is currently no effective treatment for it. Ganglion impar block and neurolytic are one methods for managing pain in such cases. Case : A 60-year-old woman with anal adenocarcinoma and chronic pain in the anal region for two years despite oral medication underwent ganglion impar block and neurolytic treatment using a mixture of 96% alcohol and levobupivacaine 0.25%. Conclusion : Ganglion impar block with neurolysis using 96% alcohol can be an option for managing perineal pain, especially when previous medication therapy is ineffective. This combination is safe for patients and can reduce pain levels.","PeriodicalId":19892,"journal":{"name":"Pharmacognosy Journal","volume":"49 9","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ganglion Impar Block and Neurolysis for Perineal Pain in Anal Adenocarcinoma: A Case Report\",\"authors\":\"Asmaranto Asmaranto, Dedi Susila\",\"doi\":\"10.5530/pj.2024.16.120\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"sides and the posterior vagina/labia minora. The patient was diagnosed with adenomakarsinoma anus and underwent 25 sessions of chemotherapy. Despite taking analgesics such as oral morphine, tramadol, codeine, and paracetamol, the patient's pain persisted with a score of 7-8 on the NRS (Numeric Rating Scale). The patient was scheduled for a ganglion impar block using a neurolytic agent ABSTRACT Background : Anal adenocarcinoma is a rare malignancy with symptoms including tenesmus, rectal bleeding, and pain during defecation. The pain can significantly reduce a patient's quality of life and there is currently no effective treatment for it. Ganglion impar block and neurolytic are one methods for managing pain in such cases. Case : A 60-year-old woman with anal adenocarcinoma and chronic pain in the anal region for two years despite oral medication underwent ganglion impar block and neurolytic treatment using a mixture of 96% alcohol and levobupivacaine 0.25%. Conclusion : Ganglion impar block with neurolysis using 96% alcohol can be an option for managing perineal pain, especially when previous medication therapy is ineffective. This combination is safe for patients and can reduce pain levels.\",\"PeriodicalId\":19892,\"journal\":{\"name\":\"Pharmacognosy Journal\",\"volume\":\"49 9\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmacognosy Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5530/pj.2024.16.120\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacognosy Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5530/pj.2024.16.120","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Ganglion Impar Block and Neurolysis for Perineal Pain in Anal Adenocarcinoma: A Case Report
sides and the posterior vagina/labia minora. The patient was diagnosed with adenomakarsinoma anus and underwent 25 sessions of chemotherapy. Despite taking analgesics such as oral morphine, tramadol, codeine, and paracetamol, the patient's pain persisted with a score of 7-8 on the NRS (Numeric Rating Scale). The patient was scheduled for a ganglion impar block using a neurolytic agent ABSTRACT Background : Anal adenocarcinoma is a rare malignancy with symptoms including tenesmus, rectal bleeding, and pain during defecation. The pain can significantly reduce a patient's quality of life and there is currently no effective treatment for it. Ganglion impar block and neurolytic are one methods for managing pain in such cases. Case : A 60-year-old woman with anal adenocarcinoma and chronic pain in the anal region for two years despite oral medication underwent ganglion impar block and neurolytic treatment using a mixture of 96% alcohol and levobupivacaine 0.25%. Conclusion : Ganglion impar block with neurolysis using 96% alcohol can be an option for managing perineal pain, especially when previous medication therapy is ineffective. This combination is safe for patients and can reduce pain levels.
期刊介绍:
In 2004, as the PHCOG.NET – a non-profit private organization dedicated to Natural Products Research leading to develop promising drugs. Our main mission is to make information on herbal drug research readily available in different formats to suit the individual needs. Pharmacognosy Journal (Phcog J.) is one of the six journals published by Phcog.Net, Each issue covers different topics in natural product drug discovery, and also publishes manuscripts that describe pharmacognostic investigations, evaluation reports, methods, techniques and applications of all forms of medicinal plant research