赞比亚卢萨卡部分综合医院妊娠诱发高血压的程度和决定因素:横断面研究

Marian Matipa Mulenga, C. Jacobs, Tinkler Saul Simbeye
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背景:妊娠高血压仍然是孕产妇和围产期发病率和死亡率的主要原因之一,影响全球5-6%的妊娠,造成严重的疾病负担:方法:对2019年1月至2020年7月期间在Chawama、Chipata和Matero三家综合医院产前门诊就诊的413名系统选取的孕妇进行横断面研究。每家医院的样本量根据 12 个月的产前检查数据按比例确定。对所有参与研究的人员进行了血压、身高、体重、体质指数和尿液分析。结构化问卷收集了有关社会人口和经济因素、生育史和病史的数据。数据使用 STATA 13 版进行分析。通过卡方检验和费氏精确检验确定 PIH 与各种变量之间的关系,并使用多元逻辑回归控制混杂因素。统计显著性设定为<0.05。结果:妊娠高血压的发病率为 21%。妊娠高血压的重要预测因素包括孕期压力(AOR = 2.28,95% CI =1.35-3.85,p=0.002)、缺乏运动(AOR = 0.48,95% CI =0.28-0.81,p=0.007)、高体重指数(AOR = 1.57,95% CI =1.12-2.19,p=0.结论:PIH 的患病率为 21%,观察到 PIH 与孕期压力、饮酒、缺乏运动和高体重指数之间存在显著关联:妊娠诱发高血压 患病率 相关因素 产前母亲
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Magnitude and Determinants of Pregnancy Induced Hypertension in Selected General Hospitals in Lusaka, Zambia: A Cross-Sectional Study
Background:Hypertension in pregnancy continue to be among the major causes of maternal and perinatal morbidity and mortality, affecting 5-6% of pregnancies globally and contributing to a significant diseaseburden. Aims and objectives: To assess prevalence and factors associated with pregnancy induced hypertension among pregnant women aged 15 to 49 years at three general hospitals of Lusaka District. Methodology:Conducted cross sectional study with 413 systematically selected pregnant women attending antenatal clinics at Chawama, Chipata and Matero general hospitals from January 2019 to July 2020. The sample size for each hospital was determined proportionally based on twelve months of antenatal care visit data. Blood pressure, heights, weights, Body mass index and urinalysis were measured on all the study participants. A structured questionnaire collected data on social demographic and economic factors, reproductive and medical history. Data was analyzed using STATA version 13. Chi-square and fisher’s exact tests identified association between PIH and various variables with multiple logistic regression used to control for confounders. Statistical significance was set at <0.05. Results:The prevalence of Pregnancy induced hypertension was found to be 21%. Significant predictors of PIH included Stress during pregnancy (AOR = 2.28, 95% CI =1.35-3.85, p=0.002), lack of exercise (AOR = 0.48, 95% CI =0.28-0.81, p=0.007), high BMI (AOR = 1.57, 95% CI =1.12-2.19, p=0.007) and consuming alcohol (AOR = 2.29, 95% CI =1.03-5.09, p=0.042).Conclusion:The prevalence of PIH was 21% with significant association observed between PIH and stress, alcohol consumption, lack of exercise and high BMI during pregnanc. Keywords: Pregnancy Induced hypertension; Prevalence; Associated factors, Antenatal mothers.
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