沿着丝线传播曲率的异化作用

Ken Sekimoto
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引用次数: 0

摘要

长丝能否在构成模块之间传递曲率并在其一端控制曲率?受原丝(微管的组成生物聚合物)观察结果的启发,我们采用一种结构性方法来解决这个问题。在我们的模型中,每个模块中的一个简单异构元件在其界面上与相邻模块耦合,从而产生了控制原丝整体形状的单一自由度。该模型可以类比于具有跨临界类型分岔的离散时间动力系统进行分析。
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Allosteric propagation of curvature along filament
Can a filament transmit the curvatures across the constituting modules and control them at one of its end? Inspired by the observation of protofilament - constituent biopolymer of microtubule - this question is addressed by a constructive approach. In our model a simple allosteric element in each module couples with the neighboring modules at its interfaces, which gives rise to a single degree of freedom to control the global shape of the filament. The model can be analyzed in analogy with discrete-time dynamical systems having a bifurcation of trans-critical type.
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