嗜酸性粒细胞食管炎患儿食管字符串检测的使用和影响:一年的经验

IF 2.4 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2024-09-01 Epub Date: 2024-07-20 DOI:10.1002/jpn3.12323
Laura A Quinn, Rachel Andrews, Maureen Bauer, Nathalie Nguyen
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引用次数: 0

摘要

1小时食管弦试验(EST)是一种微创试验,可用于监测嗜酸性粒细胞性食管炎(EoE)的疾病活动并指导治疗,而无需进行内镜检查。我们的目的是描述EST在我们中心使用的第一年中的实际使用情况及其对嗜酸性粒细胞食管炎患儿治疗的影响。在 2022 年 1 月 12 日至 2023 年 11 月 30 日期间,我们对 31 名患者进行了 45 次EST,成功实施了 39 次EST(完成率为 87%)。五名患者接受了多次EST。EST期间发生的不良事件包括呕吐。EST失败的原因(13%,n = 6)是患者无法吞咽胶囊(n = 5)和呕吐(n = 1)。在 95% 的病例(37 例)中,EST 被用于评估 EoE,而无需进行内窥镜检查。治疗方法因EST显示活动性(38.5%)或非活动性(61.5%)咽喉炎而异。EST是一种针对咽喉炎患者的耐受性良好的微创疾病监测工具。
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Utilization and impact of esophageal string testing in children with eosinophilic esophagitis: A 1 year experience.

The 1-h esophageal string test (EST) is a minimally invasive test that can be used to monitor eosinophilic esophagitis (EoE) disease activity and guide treatment without endoscopy. We aimed to describe the real-world utilization and impact of EST on the care of children with EoE over the first year this was used at our center. Between 12/1/2022 and 11/30/2023, 39 ESTs were successful in 45 attempts (87% completion rate) in 31 patients. Five patients underwent multiple ESTs. Adverse events during the EST included vomiting. Reasons for failure to complete the EST (13%, n = 6) were patients could not swallow the capsule (n = 5) and vomiting (n = 1). EST was used to assess EoE without the need for endoscopy in 95% (n = 37) of cases. Treatment approach varied based on whether the EST indicated active (38.5%) or inactive (61.5%) EoE. The EST is a well-tolerated minimally invasive disease monitoring tool for patients with EoE.

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来源期刊
CiteScore
5.30
自引率
13.80%
发文量
467
审稿时长
3-6 weeks
期刊介绍: ​The Journal of Pediatric Gastroenterology and Nutrition (JPGN) provides a forum for original papers and reviews dealing with pediatric gastroenterology and nutrition, including normal and abnormal functions of the alimentary tract and its associated organs, including the salivary glands, pancreas, gallbladder, and liver. Particular emphasis is on development and its relation to infant and childhood nutrition.
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