接纳与承诺疗法对原发性精神病住院患者精神病严重程度的疗效:随机对照试验

Mohamed Ali Zoromba, Linda Sefouhi, Atallah Alenezi, Abeer Selim, Shaimaa Awad, Heba Emad El-Gazar, Ahmed Hashem El-Monshed
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引用次数: 0

摘要

本研究调查了接纳与承诺疗法(ACT)与常规治疗相比,在控制原发性精神病住院患者的精神病症状、情绪失调、康复和心理灵活性方面的有效性。研究的主要结果是评估积极和消极综合征量表,次要结果是评估情绪调节量表、康复评估量表和接纳与行动问卷中的困难。该研究是一项开放标签、双臂平行随机对照试验。被诊断为原发性精神病的参与者被随机分配到 ACT 组(33 人)或常规治疗组(32 人)。干预措施包括六节有组织的 ACT 课程。ACT 能明显将精神病症状从 128 个减少到 104 个(Z = 5.01),而常规治疗则从 130 个减少到 117 个(Z = 4.88)。ACT 治疗组的情绪调节能力明显提高,从 73% 降至 55% (Z = 4.835),而常规治疗组则从 73% 降至 70% (Z = 2.406)。与 51 到 61(Z = 4.93)的常规治疗相比,ACT 组的恢复能力从 50 提高到 88(Z = 5.01)。心理灵活性方面,ACT 组从 33 人提高到 25 人(Z = 4.98),而常规治疗组从 33 人提高到 31 人(Z = 4.75)。在精神病症状、情绪调节、康复和心理灵活性方面,干预后的组间差异显著(Z = 2.356、4.652、3.881 和 4.453)。因此,本研究证明了 ACT 在减轻原发性精神病患者的精神症状、改善情绪调节、康复和心理灵活性方面的有效性。将 ACT 纳入标准护理方案可以提高治疗效果,为管理复杂的精神健康状况提供一种全面的方法。试验注册:ClinicalTrials.gov 标识符:NCT06160869:NCT06160869。
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Effectiveness of Acceptance and Commitment Therapy on Psychotic Severity Among Inpatients With Primary Psychoses: A Randomized Controlled Trial.

This study investigated the effectiveness of acceptance and commitment therapy (ACT) compared to treatment as usual in managing psychotic symptoms, emotional dysregulation, recovery and psychological flexibility in inpatients with primary psychoses. The Primary outcome assessed the positive and negative syndrome scale, while the secondary outcomes were to assess difficulties in the emotion regulation scale, recovery assessment scale and acceptance and action questionnaire. An open-label, two-arm parallel randomized controlled trial was conducted. Participants diagnosed with primary psychoses were randomly assigned to either the ACT (n = 33) or treatment-as-usual (n = 32) group. The intervention included six structured sessions of ACT. ACT significantly reduced psychotic symptoms from 128 to 104 (Z = 5.01) compared to treatment as usual from 130 to 117 (Z = 4.88). Emotional regulation improved significantly in the ACT group from 73 to 55 (Z = 4.835) compared to treatment as usual from 73 to 70 (Z = 2.406). Recovery increased in the ACT group from 50 to 88 (Z = 5.01) compared to treatment as usual from 51 to 61 (Z = 4.93). Psychological flexibility improved in the ACT group from 33 to 25 (Z = 4.98) compared to treatment as usual from 33 to 31 (Z = 4.75). Between-group differences after intervention were significant for psychotic symptoms, emotional regulation, recovery and psychological flexibility (Z = 2.356, 4.652, 3.881 and 4.453, respectively). Accordingly, the current study demonstrates the effectiveness of ACT in reducing psychotic symptoms and improving emotional regulation, recovery and psychological flexibility in patients with primary psychoses. Integrating ACT into standard care protocols can enhance treatment outcomes, offering a comprehensive approach to managing complex mental health conditions. Trial Registration: ClinicalTrials.gov identifier: NCT06160869.

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