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引用次数: 0
摘要
DNA 是一种被认为可以在分子水平上进行计算的纳米分子,精确的沃森-克里克碱基配对原理使 DNA 成为一种新型的计算机材料成为可能。DNA 链置换技术极大地促进了 DNA 计算在逻辑计算和智能计算方面的发展。本文提出并实现了一种基于DNA链置换的分子识别电路,可以实现识别和求和功能。该电路分子组成简单,易于扩展。在分子识别电路的基础上集成了交叉吸入模块,构建了分子比较器。考虑到模块化的优势和可扩展识别电路的实验可行性,该电路可用作智能分子电路或生物传感器中的模式信号识别和分类模块。
Scalable DNA recognition circuits based on DNA strand displacement
DNA is a kind of nano-molecule considered to be computable on the molecular level, and the precise Watson-Crick principle of base pairing has made it possible for DNA to be a novel computer material. The DNA strand displacement technology has greatly facilitated the development of DNA computing in both logical and intelligent computation. In this paper, we proposed and implemented a molecular recognition circuit based on DNA strand displacement, which can achieve recognition and summation functions. This circuit has a simple molecular composition and is easily scalable. A cross-inhalation module was integrated based upon the molecular recognition circuit to construct a molecular comparator. Considering the advantages of modularity and the experimental feasibility of scalable recognition circuit, it could be used as pattern signal recognition and classification module in smart molecular circuits or biosensors.