对全髋关节置换术后非典型感染的风险因素和炎症因素的调查:对预防和控制策略的影响。

IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Alternative therapies in health and medicine Pub Date : 2024-07-19
Qingxiu Xia, Xiaoqin Huang, Hangbo Qu, Yingzhao Yan, Zijuan Zhao
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引用次数: 0

摘要

目的该研究探讨了全髋关节置换术(THA)后鼻内感染相关因素与炎症因素之间的关系:回顾性分析2018年至2022年在浙江医院接受治疗的共296例THA患者。收集患者的临床资料,统计分析患者的院内感染率、感染部位、感染病原体、相关危险因素以及术后随访情况。疾病类型包括股骨头无血管性坏死、骨关节炎和股骨颈骨折。对三类患者手术前后的肌钙蛋白(Tn)、血常规、血型、肝素结合蛋白(HBP)、甲状腺功能、血栓弹力图(TEG)、脑钠肽(BNP)、骨代谢相关指标、糖化血红蛋白(GHb)等指标进行分析:37例(12.5%)股骨头坏死,105例(35.47%)骨关节炎,154例(52.03%)股骨颈骨折。主要感染部位为呼吸道、泌尿道、深部切口和组织感染。病原菌有 8 种,包括革兰氏阳性菌和革兰氏阴性菌。治疗后血浆中的 BNP 含量显著下降[RR:0.353(95% CI:0.234-0.533),P <.001]。术后感染患者的 HBP 明显高于未感染患者[RR:0.241 (95% CI:0.161-0.361),P < .001]。糖尿病组和非糖尿病组术后血糖均显著下降[RR:0.367 (95% CI:0.233-0.461),P < .001]。三碘甲状腺原氨酸(T3)水平呈下降趋势,而四碘甲状腺原氨酸(T4)和促甲状腺激素(TSH)均处于正常水平。术后松动 15 例,股骨干松动 6 例,髋臼松动 9 例:THA可调节和维持炎性细胞因子的平衡,针对危险因素采取预防措施可有效减少院内感染,对提高医疗质量具有重要意义。
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WITHDRAWN: An Investigation of Risk Factors and Inflammatory Factors in Nosocomial Infections Following Total Hip Arthroplasty: Implications for Prevention and Control Strategies.

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

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来源期刊
Alternative therapies in health and medicine
Alternative therapies in health and medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
0.90
自引率
0.00%
发文量
219
期刊介绍: Launched in 1995, Alternative Therapies in Health and Medicine has a mission to promote the art and science of integrative medicine and a responsibility to improve public health. We strive to maintain the highest standards of ethical medical journalism independent of special interests that is timely, accurate, and a pleasure to read. We publish original, peer-reviewed scientific articles that provide health care providers with continuing education to promote health, prevent illness, and treat disease. Alternative Therapies in Health and Medicine was the first journal in this field to be indexed in the National Library of Medicine. In 2006, 2007, and 2008, ATHM had the highest impact factor ranking of any independently published peer-reviewed CAM journal in the United States—meaning that its research articles were cited more frequently than any other journal’s in the field. Alternative Therapies in Health and Medicine does not endorse any particular system or method but promotes the evaluation and appropriate use of all effective therapeutic approaches. Each issue contains a variety of disciplined inquiry methods, from case reports to original scientific research to systematic reviews. The editors encourage the integration of evidence-based emerging therapies with conventional medical practices by licensed health care providers in a way that promotes a comprehensive approach to health care that is focused on wellness, prevention, and healing. Alternative Therapies in Health and Medicine hopes to inform all licensed health care practitioners about developments in fields other than their own and to foster an ongoing debate about the scientific, clinical, historical, legal, political, and cultural issues that affect all of health care.
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