神经免疫相互作用在过敏性鼻炎病理和发病机制中的作用。

IF 2.9 4区医学 Q3 IMMUNOLOGY Immunological Investigations Pub Date : 2024-10-01 Epub Date: 2024-07-23 DOI:10.1080/08820139.2024.2382792

Ya-An Lan, Jia-Xi Guo, Min-Hua Yao, Yi-Ting Kang, Zi-Rui Liao, Yu-Hong Jing

{"title":"神经免疫相互作用在过敏性鼻炎病理和发病机制中的作用。","authors":"Ya-An Lan, Jia-Xi Guo, Min-Hua Yao, Yi-Ting Kang, Zi-Rui Liao, Yu-Hong Jing","doi":"10.1080/08820139.2024.2382792","DOIUrl":null,"url":null,"abstract":"Background: Allergic rhinitis (AR) is a non-infectious inflammatory disease of the nasal mucosa mediated by IgE and involving a variety of immune cells such as mast cells. In previous studies, AR was considered as an isolated disease of the immune system. However, recent studies have found that the nervous system is closely related to the development of AR. Bidirectional communication between the nervous and immune systems plays an important role in AR.Summary: The nervous system and immune system depend on the anatomical relationship between nerve fibers and immune cells, as well as various neurotransmitters, cytokines, inflammatory mediators, etc. to produce bidirectional connections, which affect the development of AR.Key messages: This article reviews the impact of neuro-immune interactions in AR on the development of AR, including neuro-immune cell units.","PeriodicalId":13387,"journal":{"name":"Immunological Investigations","volume":" ","pages":"1013-1029"},"PeriodicalIF":2.9000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Role of Neuro-Immune Interactions in the Pathology and Pathogenesis of Allergic Rhinitis.\",\"authors\":\"Ya-An Lan, Jia-Xi Guo, Min-Hua Yao, Yi-Ting Kang, Zi-Rui Liao, Yu-Hong Jing\",\"doi\":\"10.1080/08820139.2024.2382792\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Allergic rhinitis (AR) is a non-infectious inflammatory disease of the nasal mucosa mediated by IgE and involving a variety of immune cells such as mast cells. In previous studies, AR was considered as an isolated disease of the immune system. However, recent studies have found that the nervous system is closely related to the development of AR. Bidirectional communication between the nervous and immune systems plays an important role in AR.Summary: The nervous system and immune system depend on the anatomical relationship between nerve fibers and immune cells, as well as various neurotransmitters, cytokines, inflammatory mediators, etc. to produce bidirectional connections, which affect the development of AR.Key messages: This article reviews the impact of neuro-immune interactions in AR on the development of AR, including neuro-immune cell units.\",\"PeriodicalId\":13387,\"journal\":{\"name\":\"Immunological Investigations\",\"volume\":\" \",\"pages\":\"1013-1029\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Immunological Investigations\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/08820139.2024.2382792\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/7/23 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunological Investigations","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/08820139.2024.2382792","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/23 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

背景：过敏性鼻炎（AR）是一种由 IgE 介导、肥大细胞等多种免疫细胞参与的鼻粘膜非感染性炎症性疾病。在以往的研究中，AR 被认为是一种孤立的免疫系统疾病。然而，最近的研究发现，神经系统与 AR 的发病密切相关。神经系统和免疫系统之间的双向交流在AR中起着重要作用。摘要：神经系统和免疫系统依赖于神经纤维和免疫细胞之间的解剖关系，以及各种神经递质、细胞因子、炎症介质等产生双向联系，从而影响AR的发生发展：本文综述了AR中神经-免疫相互作用对AR发育的影响，包括神经-免疫细胞单元。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

The Role of Neuro-Immune Interactions in the Pathology and Pathogenesis of Allergic Rhinitis.

Background: Allergic rhinitis (AR) is a non-infectious inflammatory disease of the nasal mucosa mediated by IgE and involving a variety of immune cells such as mast cells. In previous studies, AR was considered as an isolated disease of the immune system. However, recent studies have found that the nervous system is closely related to the development of AR. Bidirectional communication between the nervous and immune systems plays an important role in AR.

Summary: The nervous system and immune system depend on the anatomical relationship between nerve fibers and immune cells, as well as various neurotransmitters, cytokines, inflammatory mediators, etc. to produce bidirectional connections, which affect the development of AR.

Key messages: This article reviews the impact of neuro-immune interactions in AR on the development of AR, including neuro-immune cell units.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Immunological Investigations 医学-免疫学

CiteScore

5.50

自引率

7.10%

发文量

审稿时长

3 months

期刊介绍： Disseminating immunological developments on a worldwide basis, Immunological Investigations encompasses all facets of fundamental and applied immunology, including immunohematology and the study of allergies. This journal provides information presented in the form of original research articles and book reviews, giving a truly in-depth examination of the latest advances in molecular and cellular immunology.