储备纳洛酮的相关因素:对社区药剂师的横断面调查。

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY International Journal of Clinical Pharmacy Pub Date : 2024-12-01 Epub Date: 2024-07-23 DOI:10.1007/s11096-024-01773-3
Rose Laing, Ting Xia, Elizabeth Grist, Jana Dostal, Suzanne Nielsen, Louisa Picco
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引用次数: 0

摘要

背景:提供可带回家的纳洛酮(THN)和用药过量教育可降低阿片类药物相关死亡率。在澳大利亚,自 2022 年 7 月起,所有澳大利亚社区药房都有资格通过国家 THN 计划免费提供纳洛酮。目的:本研究旨在确定澳大利亚药房的纳洛酮库存率以及库存纳洛酮的相关因素:通过在线调查从维多利亚州、新南威尔士州、昆士兰州和西澳大利亚州具有代表性的澳大利亚药剂师样本中收集数据。收集的数据包括药房和药剂师的特征以及药房内提供的服务,包括针头和注射器计划、阿片类激动剂治疗(OAT)和纳洛酮储备。在控制主要协变量后,采用二元概率回归分析确定纳洛酮储备的相关因素:对 530 名药剂师的数据进行了分析。共有 321 家药店(60.6%)报告储存了纳洛酮。连锁药店和提供 OAT 的药店储存纳洛酮的概率更高(B = 0.307,95%CI:[0.057, 0.556];B = 0.543,95%CI:[0.308, 0.777])。大多数(61.7%)药剂师在与使用处方阿片类药物的患者讨论预防用药过量问题时感到轻松自如,这种轻松自如与储备纳洛酮的可能性较高相关(B = 0.392,95%CI:0.128,0.655)。与使用非法阿片类药物者讨论预防药物过量的舒适度较低(49.4%),与储备纳洛酮无关:结论:纳洛酮的储备量和对预防用药过量的舒适度都有提高的空间,特别是通过解决与高风险群体(如使用非法阿片类药物者)合作的舒适度问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Correlates of stocking naloxone: a cross-sectional survey of community pharmacists.

Background: Provision of take-home naloxone (THN) and overdose education reduces opioid-related mortality. In Australia, from July 2022, all Australian community pharmacies were eligible to supply naloxone for free through the national THN Program.

Aim: This study aimed to identify naloxone stocking rates and correlates of stocking naloxone across Australian pharmacies.

Method: Data were collected from a representative sample of Australian pharmacists in Victoria, New South Wales, Queensland and Western Australia via an online survey. Data collected included pharmacy and pharmacist characteristics and services offered within the pharmacy, including needle and syringe programs, opioid agonist treatment (OAT) and stocking naloxone. Binary probit regression analysis was used to identify correlates of stocking naloxone after controlling for key covariates.

Results: Data from 530 pharmacists were analysed. In total, 321 pharmacies (60.6%) reported stocking naloxone. Chain pharmacies and pharmacies that provided OAT had a greater probability of stocking naloxone (B = 0.307, 95%CI: [0.057, 0.556], and B = 0.543, 95%CI: [0.308, 0.777] respectively). Most (61.7%) pharmacists felt comfortable discussing overdose prevention with patients who use prescription opioids, and this comfort was associated with a higher probability of stocking naloxone (B = 0.392, 95%CI: 0.128, 0.655). Comfort discussing overdose prevention with people who use illicit opioids was lower (49.4%) and was not associated with stocking naloxone.

Conclusion: There is scope to increase stocking of naloxone and comfort with overdose prevention, particularly through addressing comfort working with higher risk groups such as people who use illicit opioids.

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来源期刊
CiteScore
4.10
自引率
8.30%
发文量
131
审稿时长
4-8 weeks
期刊介绍: The International Journal of Clinical Pharmacy (IJCP) offers a platform for articles on research in Clinical Pharmacy, Pharmaceutical Care and related practice-oriented subjects in the pharmaceutical sciences. IJCP is a bi-monthly, international, peer-reviewed journal that publishes original research data, new ideas and discussions on pharmacotherapy and outcome research, clinical pharmacy, pharmacoepidemiology, pharmacoeconomics, the clinical use of medicines, medical devices and laboratory tests, information on medicines and medical devices information, pharmacy services research, medication management, other clinical aspects of pharmacy. IJCP publishes original Research articles, Review articles , Short research reports, Commentaries, book reviews, and Letters to the Editor. International Journal of Clinical Pharmacy is affiliated with the European Society of Clinical Pharmacy (ESCP). ESCP promotes practice and research in Clinical Pharmacy, especially in Europe. The general aim of the society is to advance education, practice and research in Clinical Pharmacy . Until 2010 the journal was called Pharmacy World & Science.
期刊最新文献
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