球部尿道成形术技术与狭窄复发:端对端尿道成形术与使用移植物的区别。

IF 4.9 2区 医学 Q1 UROLOGY & NEPHROLOGY Minerva Urology and Nephrology Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI:10.23736/S2724-6051.24.05812-9
Fernando Alberca-Del Arco, Rocío Santos-Pérez DE LA Blanca, Carmen Amores Vergara, Bernardo Herrera-Imbroda, Felipe Sáez-Barranquero
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引用次数: 0

摘要

尿道狭窄(US)最常影响尿道的前段,具体来说就是球部,男性发病率很高。开放式尿道成形术是金标准治疗方法。然而,尿道狭窄复发(SR)仍然是当前令人担忧的问题。本综述旨在提供有关球部 US 尿道成形手术技术和 SR 预后因素的最新文献摘要,并对不同方法进行比较。对于较短的狭窄,切除和原位吻合术(EPA)是首选,成功率超过 90%。对于较长的狭窄(>2-3 厘米),通常需要采用替代技术。颊粘膜移植(BMG)仍是首选,因为它符合理想的特征,而且移植部位没有明显差异。尿道狭窄的长度、尿道成形术后的时间以及之前尿道介入治疗的次数是导致失败的风险因素。此外,外科医生的经验也会影响技术选择和未来结果。与 EPA 相比,替代技术的 SR 率更高,这一点似乎已达成共识,但这似乎受狭窄长度的影响,前者的狭窄长度通常更长。此外,有一种趋势倾向于采用内窥镜治疗 SR,但对于长而复杂的复发,则应使用移植物。总之,目前有多种尿道成形术可供选择,必须根据狭窄特点、患者病史和外科医生的经验进行个体化选择。目前仍有必要开展设计合理、定义明确的研究并制定随访方案,以便为球部 US 的治疗制定标准化指南。
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Bulbar urethroplasty techniques and stricture recurrence: differences between end-to-end urethroplasty versus the use of graft.

Urethral stricture (US) affects most commonly the anterior portion of the urethra, concretely the bulbar, with a significant incidence in men. Open urethroplasty is the gold standard treatment. However, stricture recurrence (SR) remains a current subject of concern. The aim of the present review is to provide an updated literature summary on surgical urethroplasty techniques for bulbar US and prognostic factors for SR, comparing the different approaches. For short strictures, excision and primary anastomosis (EPA) is the preferred option, with success rates exceeding 90%. Substitution techniques are usually required for longer strictures (>2-3cm). Buccal mucosa graft (BMG) remains the first choice as it complies with ideal features, with no significant differences regarding the site of graft implantation. Stricture length, time since urethroplasty and number of previous urethral interventions are risk factors for failure. Also, surgeon's experience affects technique selection and future outcomes. There seems to be consensus on a higher SR rate following substitution techniques compared to EPA, which appears to be influenced by the stricture length, usually longer in the former group. Furthermore, there is a trend in favor of endoscopic management of SR, except for long and complex recurrences where grafts should be used. In conclusion, multiple urethroplasty techniques are available and selection must be carefully individualized, focusing on stricture characteristics, patient's history, and surgeon's experience. Well-designed studies with clear definitions and follow-up protocols are still necessary to develop standardized guidelines on the management of bulbar US.

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来源期刊
Minerva Urology and Nephrology
Minerva Urology and Nephrology UROLOGY & NEPHROLOGY-
CiteScore
8.50
自引率
32.70%
发文量
237
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