{"title":"处于次优妊娠环境中的儿童在运动过程中的生理反应得以保持。","authors":"Soraya Saidj, Stephanie-May Ruchat, Mélanie Henderson, Angelo Tremblay, Marie-Eve Mathieu","doi":"10.1002/oby.24049","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>This study investigated whether exposure to suboptimal gestational factors (SGFs) alters mechanical efficiency (ME) and substrate oxidation during rest and exercise in children as a mechanism contributing to obesity.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Data from the Quebec Adiposity and Lifestyle Investigation in Youth cohort were used. Children aged 8 to 10 years performed an incremental maximal cycling test with indirect calorimetry. Their ME was measured during submaximal and maximal effort. The substrate oxidation during rest and submaximal effort was also computed. ME and substrate oxidation results between children exposed to each SGF during pregnancy (gestational diabetes mellitus: <i>n</i> = 68; hypertensive disorders: <i>n</i> = 49; maternal smoking: <i>n</i> = 77) and nonexposed children (<i>n</i> = 370) were compared.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>No difference was observed for ME during submaximal (<i>F</i><sub>[3,540]</sub> = 0.46, <i>p</i> = 0.713) and maximal effort (<i>F</i><sub>[3,545]</sub> = 0.86, <i>p</i> = 0.463) between exposed and nonexposed children. The percentage contributions of lipids and carbohydrates did not differ during rest (<i>F</i><sub>[3,545]</sub> =1.68, <i>p</i> = 0.169) or submaximal exercise (<i>F</i><sub>[3,544]</sub> = 0.31, <i>p</i> = 0.534) between exposed and nonexposed children.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Children exposed to investigated SGFs display a similar physiological response regarding ME and substrate oxidation during rest and exercise compared to nonexposed children. Future studies should confirm these novel results and continue investigating other research avenues to explain the higher risk of obesity in this population.</p>\n </section>\n </div>","PeriodicalId":215,"journal":{"name":"Obesity","volume":null,"pages":null},"PeriodicalIF":4.2000,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.24049","citationCount":"0","resultStr":"{\"title\":\"Physiological response during exercise is preserved in children exposed to a suboptimal gestational environment\",\"authors\":\"Soraya Saidj, Stephanie-May Ruchat, Mélanie Henderson, Angelo Tremblay, Marie-Eve Mathieu\",\"doi\":\"10.1002/oby.24049\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>This study investigated whether exposure to suboptimal gestational factors (SGFs) alters mechanical efficiency (ME) and substrate oxidation during rest and exercise in children as a mechanism contributing to obesity.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Data from the Quebec Adiposity and Lifestyle Investigation in Youth cohort were used. Children aged 8 to 10 years performed an incremental maximal cycling test with indirect calorimetry. Their ME was measured during submaximal and maximal effort. The substrate oxidation during rest and submaximal effort was also computed. ME and substrate oxidation results between children exposed to each SGF during pregnancy (gestational diabetes mellitus: <i>n</i> = 68; hypertensive disorders: <i>n</i> = 49; maternal smoking: <i>n</i> = 77) and nonexposed children (<i>n</i> = 370) were compared.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>No difference was observed for ME during submaximal (<i>F</i><sub>[3,540]</sub> = 0.46, <i>p</i> = 0.713) and maximal effort (<i>F</i><sub>[3,545]</sub> = 0.86, <i>p</i> = 0.463) between exposed and nonexposed children. The percentage contributions of lipids and carbohydrates did not differ during rest (<i>F</i><sub>[3,545]</sub> =1.68, <i>p</i> = 0.169) or submaximal exercise (<i>F</i><sub>[3,544]</sub> = 0.31, <i>p</i> = 0.534) between exposed and nonexposed children.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Children exposed to investigated SGFs display a similar physiological response regarding ME and substrate oxidation during rest and exercise compared to nonexposed children. Future studies should confirm these novel results and continue investigating other research avenues to explain the higher risk of obesity in this population.</p>\\n </section>\\n </div>\",\"PeriodicalId\":215,\"journal\":{\"name\":\"Obesity\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2024-07-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.24049\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Obesity\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/oby.24049\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obesity","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/oby.24049","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
摘要
目的：本研究探讨了次优妊娠因素（SGFs）是否会改变儿童在休息和运动时的机械效率（ME）和底物氧化，从而导致肥胖：本研究探讨了暴露于次优妊娠因素（SGFs）是否会改变儿童在休息和运动时的机械效率（ME）和底物氧化，并将其作为导致肥胖的一种机制：方法：采用魁北克青少年肥胖和生活方式调查队列的数据。8至10岁的儿童通过间接热量计进行了增量最大骑行测试。测量了他们在次最大努力和最大努力时的 ME 值。此外，还计算了休息和次最大努力时的底物氧化。比较了孕期暴露于每种 SGF 的儿童（妊娠糖尿病：n = 68；高血压疾病：n = 49；母亲吸烟：n = 77）和未暴露于 SGF 的儿童（n = 370）的 ME 和底物氧化结果：结果表明：在亚极限（F[3,540] = 0.46，p = 0.713）和极限（F[3,545] = 0.86，p = 0.463）时，暴露和非暴露儿童的 ME 没有差异。在休息期间（F[3,545] =1.68，p =0.169）或亚极限运动期间（F[3,544] =0.31，p =0.534），暴露与非暴露儿童的脂类和碳水化合物贡献百分比没有差异：结论：与未暴露于所调查的 SGFs 的儿童相比，暴露于这些 SGFs 的儿童在休息和运动时的 ME 和底物氧化方面表现出相似的生理反应。未来的研究应确认这些新结果，并继续探索其他研究途径，以解释该人群肥胖风险较高的原因。
Physiological response during exercise is preserved in children exposed to a suboptimal gestational environment
Objective
This study investigated whether exposure to suboptimal gestational factors (SGFs) alters mechanical efficiency (ME) and substrate oxidation during rest and exercise in children as a mechanism contributing to obesity.
Methods
Data from the Quebec Adiposity and Lifestyle Investigation in Youth cohort were used. Children aged 8 to 10 years performed an incremental maximal cycling test with indirect calorimetry. Their ME was measured during submaximal and maximal effort. The substrate oxidation during rest and submaximal effort was also computed. ME and substrate oxidation results between children exposed to each SGF during pregnancy (gestational diabetes mellitus: n = 68; hypertensive disorders: n = 49; maternal smoking: n = 77) and nonexposed children (n = 370) were compared.
Results
No difference was observed for ME during submaximal (F[3,540] = 0.46, p = 0.713) and maximal effort (F[3,545] = 0.86, p = 0.463) between exposed and nonexposed children. The percentage contributions of lipids and carbohydrates did not differ during rest (F[3,545] =1.68, p = 0.169) or submaximal exercise (F[3,544] = 0.31, p = 0.534) between exposed and nonexposed children.
Conclusions
Children exposed to investigated SGFs display a similar physiological response regarding ME and substrate oxidation during rest and exercise compared to nonexposed children. Future studies should confirm these novel results and continue investigating other research avenues to explain the higher risk of obesity in this population.
期刊介绍：
Obesity is the official journal of The Obesity Society and is the premier source of information for increasing knowledge, fostering translational research from basic to population science, and promoting better treatment for people with obesity. Obesity publishes important peer-reviewed research and cutting-edge reviews, commentaries, and public health and medical developments.
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