面部色素沉着：阿达木单抗的罕见副作用

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI:10.1177/23247096241265896

Malek Mrad, Mariam Tabka, Asmahane Souissi, Ines Chelly, Mourad Mokni

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引用次数: 0

摘要

本报告描述了一例接受肿瘤坏死因子（TNF）-α抑制剂阿达木单抗治疗的克罗恩病患者的面部色素沉着病例。色素沉着的发病时间与阿达木单抗的用药时间一致，停药后病情明显好转。组织病理学结果表明，真皮-表皮交界处存在炎症后过程。然而，确切的机制仍不清楚。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Facial Hyperpigmentation: A Rare Side Effect of Adalimumab.

This report describes a case of facial hyperpigmentation in a patient with Crohn's disease receiving adalimumab, a tumor necrosis factor (TNF)-alpha inhibitor. The onset of hyperpigmentation coincided with adalimumab administration, and its discontinuation resulted in significant improvement. Histopathological findings suggest a postinflammatory process at the dermo-epidermal junction. However, the precise mechanism remains unclear.

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来源期刊

Journal of investigative medicine high impact case reports MEDICINE, GENERAL & INTERNAL-

CiteScore

1.90

自引率

0.00%

发文量

165

审稿时长

12 weeks

期刊介绍： The AFMR is committed to enhancing the training and career development of our members and to furthering its mission to facilitate the conduct of research to improve medical care. Case reports represent an important avenue for trainees (interns, residents, and fellows) and early-stage faculty to demonstrate productive, scholarly activity.