挪威一所中型大学医院二尖瓣修复术治疗瓣叶脱垂的五年疗效。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-12-01 Epub Date: 2024-07-25 DOI:10.1080/14017431.2024.2379336
Trym Løvseth Kavlie, Henrik Agerup Kildahl, Håvard Dalen, Dag Ole Nordhaug, Katrine Hordnes Slagsvold, Bjørnar Leangen Grenne, Espen Holte
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引用次数: 0

摘要

目的。评估一家中型心胸中心的二尖瓣(MV)脱垂患者特征和二尖瓣手术修复后的 5 年疗效。背景。有关中型心胸中心二尖瓣修复术疗效的当代报道很少。方法。纳入 2015 年至 2021 年期间因小叶脱垂引起的原发性二尖瓣反流而接受中风修补开胸手术,且无活动性心内膜炎的患者。临床数据、并发症、再次干预、死亡率和超声心动图数据均通过电子病历进行回顾性登记,包括术前和术后随访。结果。共纳入 103 名患者,其中 83% 为男性,平均年龄为 62 岁。中位随访时间为 4.9 年,全因死亡率为 9%。MV 的再次介入率为 4%。在中位 3.0 年的最后一次随访之前,术后并发症并不常见,其中 16% 的患者出现新发心房颤动/搏动,17% 的患者术后出现二尖瓣反流 II 级或以上,14% 的患者术后出现三尖瓣反流 II 级或以上。结论。这些数据表明,在一个中等规模的心胸中心进行中上叶脱垂手术修复,再介入率低,严重并发症少。所提供的结果与手术量大的中心的数据相当,表明在选定的中型心胸中心可以安全地进行中上叶修复手术。
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Five-year outcomes of mitral valve repair for leaflet prolapse at a medium-sized Norwegian university hospital.

Objective. To evaluate patient characteristics and 5-year outcomes after surgical mitral valve (MV) repair for leaflet prolapse at a medium-sized cardiothoracic center. Background. Contemporary reports on the outcome of MV repair at medium-sized cardiothoracic centers are sparse. Methods. Patients receiving open-heart surgery with MV repair due to primary mitral regurgitation caused by leaflet prolapse between 2015 and 2021, without active endocarditis, were included. Clinical data, complications, re-interventions, mortality, and echocardiographic data were retrospectively registered from electronical patient charts, both pre-operatively and from post-operative follow-ups. Results. One hundred and three patients were included, 83% male, with a mean age of 62 years. All-cause mortality was 9% during a median follow-up time of 4.9 years. Re-intervention rate on the MV was 4%. Post-operative complications before last available follow-up visit at median 3.0 years were infrequent, with new-onset atrial fibrillation/flutter in 16%, post-operative MV regurgitation grade II or above in 17% and post-operative tricuspid regurgitation grade II or above in 14%. Conclusions. These data demonstrate that surgical MV repair for leaflet prolapse at a medium-sized cardiothoracic center was associated with low re-intervention rate and few severe complications. The presented results are comparable to data from surgical high-volume centers, indicating that surgical MV repair can be safely performed at selected medium-sized cardiothoracic centers.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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