利用多尺度视觉转换器架构和改进的语言对冲神经模糊分类器预测孕产妇甲状腺疾病的新方法。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.3233/THC-240362
Summia Parveen H, Karthik S, Sabitha R
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引用次数: 0

摘要

背景:对母亲进行孕早期甲状腺功能评估的范围很广。使用负荷特异性参考范围的好处已得到证实:我们在思考,如果使用孕早期获得的多个血液样本,母体甲状腺功能的分类是否会发生变化。尽管二元分类是目前疾病诊断技术的共同目标,但数据集很小,结果也未经验证。目前的大多数方法都集中于模型优化,而较少关注特征工程:建议的方法可以预测蛋白质结合力增高、非甲状腺综合征(NTIS)(同时患有非甲状腺疾病)、自身免疫性甲状腺炎(代偿性甲减)和桥本氏甲状腺炎(原发性甲减)。本文利用多尺度视觉变换器和图像增强技术开发了甲状腺结节自动分类系统。图均衡化是我们选择的图像增强技术,在实验中,我们使用了四层网络节点的神经网络。这项工作提出了一种增强型语言覆盖神经模糊分类器,其所选特征用于甲状腺疾病特征选择诊断。优化了训练程序,并采用了多尺度视觉转换器网络。现在,密集网络中的每一跳连接都有可训练的权重参数,从而改变了结构。来自 508 名患者的甲状腺结节图像构成了本文的数据集。我们从这些数据中创建了 80% 训练和 20% 验证集,以及 70% 训练和 30% 验证集。同时,我们还考虑了训练迭代次数、网络结构、网络节点的激活函数等因素对分类结果的影响:根据实验结果,最佳训练迭代次数为 500 次,Logistic 函数是最佳激活函数,理想的网络结构为 2500-40-2-1:结论:K 倍验证以及与之前研究的性能对比验证了所建议方法的有效性。
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A novel maternal thyroid disease prediction using multi-scale vision transformer architecture with improved linguistic hedges neural-fuzzy classifier.

Background: Early pregnancy thyroid function assessment in mothers is covered. The benefits of using load-specific reference ranges are well-established.

Objective: We pondered whether the categorization of maternal thyroid function would change if multiple blood samples obtained early in pregnancy were used. Even though binary classification is a common goal of current disease diagnosis techniques, the data sets are small, and the outcomes are not validated. Most current approaches concentrate on model optimization, focusing less on feature engineering.

Methods: The suggested method can predict increased protein binding, non-thyroid syndrome (NTIS) (simultaneous non-thyroid disease), autoimmune thyroiditis (compensated hypothyroidism), and Hashimoto's thyroiditis (primary hypothyroidism). In this paper, we develop an automatic thyroid nodule classification system using a multi-scale vision transformer and image enhancement. Graph equalization is the chosen technique for image enhancement, and in our experiments, we used neural networks with four-layer network nodes. This work presents an enhanced linguistic coverage neuro-fuzzy classifier with chosen features for thyroid disease feature selection diagnosis. The training procedure is optimized, and a multi-scale vision transformer network is employed. Each hop connection in Dense Net now has trainable weight parameters, altering the architecture. Images of thyroid nodules from 508 patients make up the data set for this article. Sets of 80% training and 20% validation and 70% training and 30% validation are created from the data. Simultaneously, we take into account how the number of training iterations, network structure, activation function of network nodes, and other factors affect the classification outcomes.

Results: According to the experimental results, the best number of training iterations is 500, the logistic function is the best activation function, and the ideal network structure is 2500-40-2-1.

Conclusion: K-fold validation and performance comparison with previous research validate the suggested methodology's enhanced effectiveness.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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