Evan S Drake, Adriane B Marino, Jenna D Theroux, Kaitlin Roberts
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引用次数: 0
摘要
摘要：在过去十年中，胰高血糖素样肽-1（GLP-1）受体激动剂（RA）类药物彻底改变了 2 型糖尿病及其一些合并症（包括肥胖症和心血管疾病）的治疗方法。GLP-1 RA 领域的不断进步为患者带来了临床希望，但同时也存在着挑战，包括药物费用和可用性等治疗障碍。本文概述了现有的 GLP-1 RA 及其作用机制、适应症、不良反应和风险，并为医疗服务提供者提供了实用的指南。
GLP-1 RAs: The newest powerhouse in metabolic medicine.
Abstract: In the last decade, the glucagon-like peptide-1 (GLP-1) receptor agonist (RA) drug class has revolutionized treatment for type 2 diabetes mellitus and some of its comorbidities, including obesity and cardiovascular disease. Continued advancements in the GLP-1 RA space show clinical promise for patients, though challenges-including barriers to care such as drug expense and availability-exist. This article provides an overview of available GLP-1 RAs and their mechanisms of action, indications, adverse reactions, and risks, providing practical pearls for providers along the way.
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With a circulation of 20,000, The Nurse Practitioner is the leading monthly source for clinical, practical, cutting-edge information for advanced practice nurses and other primary care clinicians. Each issue presents peer-reviewed articles that range from clinical topics and research to political and practice issues. In addition, The Nurse Practitioner provides regular features, columns, continuing education, staff development education, and more.
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