伪装成血色素沉着病的新生儿巴塞杜氏病

JCEM case reports Pub Date : 2024-07-24 eCollection Date: 2024-07-01 DOI:10.1210/jcemcr/luae132
Liesbeth Maggiotto, Steven D Mittelman, Roja Fallah
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引用次数: 0

摘要

甲状腺自身免疫在成年人群中极为常见,并可能影响妊娠结果。新生儿的体征可从无症状到严重症状不等,因此很容易漏诊。我们介绍了一例有趣的新生儿巴塞杜氏病病例,该病例伴有宫内生长受限、早产、肝功能衰竭和严重的高铁蛋白,被认为是继发于血色素沉着病。对潜在的甲状腺功能亢进症进行治疗后,铁蛋白升高和肝功能衰竭迅速缓解。该报告强调了在病因不明的新生儿肝衰竭中考虑巴塞杜氏病的重要性。
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Neonatal Graves Disease Masquerading as Hemochromatosis.

Thyroid autoimmunity is extremely common in the adult population and can affect pregnancy outcomes. Signs in the newborn can range from absent to severe, making the diagnosis easy to miss. We present an interesting case of neonatal Graves disease associated with intrauterine growth restriction, premature delivery, and liver failure with severely high ferritin, thought to be secondary to hemochromatosis. Treatment of the underlying hyperthyroidism caused a rapid resolution of the elevated ferritin and liver failure. This report highlights the importance of considering Graves disease in newborns with liver failure of unknown etiology.

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