病毒模仿和内分泌系统:揭示宿主-微生物串扰的重要性

3区 生物学 Q1 Biochemistry, Genetics and Molecular Biology Advances in protein chemistry and structural biology Pub Date : 2024-01-01 Epub Date: 2024-07-04 DOI:10.1016/bs.apcsb.2024.03.005
Elora Kalita, Mamta Panda, Abhishek Rao, Rajan Kumar Pandey, Vijay Kumar Prajapati
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引用次数: 0

摘要

宿主与病原体之间的相互作用是一种复杂的关联,在漫长的共同进化史中不断演化。病原体表现出不同的机制来获得对宿主的优势。模仿宿主因子是颠覆宿主机制以确保致病性的一种有影响力的工具。本章将讨论病毒感染过程中表现出的分子模仿。了解病毒编码模拟物的进化关系、共同特征和功能影响至关重要。本章特别强调病毒拟态及其与癌症和自身免疫性疾病的关系,突出了分子拟态在病毒生物学中的重要性。
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Viral mimicry and endocrine system: Divulging the importance in host-microbial crosstalk.

Host-pathogen interactions are complex associations which evolve over long co-evolutionary histories. Pathogens exhibit different mechanisms to gain advantage over their host. Mimicry of host factors is an influential tool in subverting host mechanisms to ensure pathogenesis. This chapter discusses such molecular mimicry exhibited during viral infections. Understanding the evolutionary relationships, shared identity and functional impact of the virus encoded mimics is critical. With a particular emphasis on viral mimics and their association with cancer and autoimmune diseases, this chapter highlights the importance of molecular mimicry in virus biology.

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来源期刊
Advances in protein chemistry and structural biology
Advances in protein chemistry and structural biology BIOCHEMISTRY & MOLECULAR BIOLOGY-
CiteScore
7.40
自引率
0.00%
发文量
66
审稿时长
>12 weeks
期刊介绍: Published continuously since 1944, The Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.
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