{"title":"可重复使用催化剂 (Bu3Sn)2MoO4 促进 3-芳基甲基吲哚的高效一步合成","authors":"Chiranjeevi Yakkanti, Vaikunta Rao Lakinani, Sathish Kumar Burra, Simhachalam Gorle, R Venkateswarlu, Raghunadh Akula","doi":"10.1007/s12039-024-02289-z","DOIUrl":null,"url":null,"abstract":"<div><p>An efficient multi-component protocol for synthesizing substituted 3-arylmethyl indoles derivatives through a three-component strategy using water: ethanol (H<sub>2</sub>O:EtOH) at 45–50°C with good to excellent yields. The main advantages of this protocol are mild reaction conditions, easy workup, and recyclability of the catalyst for up to four catalytic cycles.</p><h3>Graphical abstract</h3><p> Synopsis: Synthesis of substituted 3-arylmethyl indoles by using efficient multi-component strategy in ethanol: water as a solvent system by using (Bu<sub>3</sub>Sn)<sub>2</sub>MoO<sub>4</sub> as a reusable catalyst at 45–50 °C with good to excellent yields. The catalyst is reusable in four catalytic cycles.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":616,"journal":{"name":"Journal of Chemical Sciences","volume":"136 3","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Efficient one-pot synthesis of 3-arylmethyl indoles promoted by (Bu3Sn)2MoO4 as a reusable catalyst\",\"authors\":\"Chiranjeevi Yakkanti, Vaikunta Rao Lakinani, Sathish Kumar Burra, Simhachalam Gorle, R Venkateswarlu, Raghunadh Akula\",\"doi\":\"10.1007/s12039-024-02289-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>An efficient multi-component protocol for synthesizing substituted 3-arylmethyl indoles derivatives through a three-component strategy using water: ethanol (H<sub>2</sub>O:EtOH) at 45–50°C with good to excellent yields. The main advantages of this protocol are mild reaction conditions, easy workup, and recyclability of the catalyst for up to four catalytic cycles.</p><h3>Graphical abstract</h3><p> Synopsis: Synthesis of substituted 3-arylmethyl indoles by using efficient multi-component strategy in ethanol: water as a solvent system by using (Bu<sub>3</sub>Sn)<sub>2</sub>MoO<sub>4</sub> as a reusable catalyst at 45–50 °C with good to excellent yields. The catalyst is reusable in four catalytic cycles.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":616,\"journal\":{\"name\":\"Journal of Chemical Sciences\",\"volume\":\"136 3\",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-07-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Chemical Sciences\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s12039-024-02289-z\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chemical Sciences","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s12039-024-02289-z","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Efficient one-pot synthesis of 3-arylmethyl indoles promoted by (Bu3Sn)2MoO4 as a reusable catalyst
An efficient multi-component protocol for synthesizing substituted 3-arylmethyl indoles derivatives through a three-component strategy using water: ethanol (H2O:EtOH) at 45–50°C with good to excellent yields. The main advantages of this protocol are mild reaction conditions, easy workup, and recyclability of the catalyst for up to four catalytic cycles.
Graphical abstract
Synopsis: Synthesis of substituted 3-arylmethyl indoles by using efficient multi-component strategy in ethanol: water as a solvent system by using (Bu3Sn)2MoO4 as a reusable catalyst at 45–50 °C with good to excellent yields. The catalyst is reusable in four catalytic cycles.
期刊介绍：
Journal of Chemical Sciences is a monthly journal published by the Indian Academy of Sciences. It formed part of the original Proceedings of the Indian Academy of Sciences – Part A, started by the Nobel Laureate Prof C V Raman in 1934, that was split in 1978 into three separate journals. It was renamed as Journal of Chemical Sciences in 2004. The journal publishes original research articles and rapid communications, covering all areas of chemical sciences. A significant feature of the journal is its special issues, brought out from time to time, devoted to conference symposia/proceedings in frontier areas of the subject, held not only in India but also in other countries.
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