用于放疗剂量测定的 myOSLchip 系统的临床验证

H. Davis, J. Siebers, K. Wijesooriya, M. Mistro
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摘要

在放射肿瘤学中,通常使用发光剂量计进行点间剂量测定,以验证计划的准确性,并确保患者的安全。光激发发光探测器(OSLD)是最常用的探测器类型,在兆伏能量范围内具有良好的剂量线性和准确性。弗莱贝格仪器公司提供了一种剂量测定系统,品牌名称为 myOLSchip,由 BeO OSL 剂量计、读数器和橡皮擦组成。使用瓦里安 Truebeam 对探测器进行鉴定并校准其响应,以便在治疗过程中进行原位剂量测定。分别用 6-15MV 和 6-20MV 的光子束和电子束对 OSLD 进行了测试。在这项研究中,剂量信号与剂量之间的转换遵循了 TG-191 的建议,即为每个剂量计绘制剂量反应曲线并创建批量校准因子。此外,还对该系统在连续擦除和重新辐照周期后的耐受性进行了研究。这些数据的结果与 BeO 探测器制造商所宣称的准确度和精确度进行了比较,结果表明,在多次照射和擦除周期中,BeO 探测器具有良好的剂量线性和可重复性。
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Clinical Validation of myOSLchip system for Radiotherapy Dosimetry
In radiation oncology, inter-fractional dosimetry is often performed with luminescent dosimeters to verify the accurate delivery of a plan and ensure patient safety. Optically stimulated luminescent detectors (OSLDs) are the most commonly used detector type which offers good dose linearity and accuracy in the megavoltage energy range. Freiberg Instruments offer a dosimetry system under the brand name myOLSchip which consists of a BeO OSL dosimeter, reader, and eraser. A Varian Truebeam was used to characterize the detectors and calibrate their response in order to perform in-situ dosimetry during treatment. The OSLDs were tested with both photon and electron beams from 6-15 MV and 6-20 MV respectively. The dose signal to dose conversion in this investigation follows the recommendations of TG-191 in developing a dose response curve and creating a batch calibration factor for each dosimeter. The repeatability of this system is also investigated following successive erasing and re-irradiation cycles. The results of this data have been compared to the stated accuracy and precision of the BeO detectors by the manufacturer and shown to have good dose linearity and repeatability across multiple exposures and erasure cycles.
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