多中心研究:伴有精神障碍的电晕病毒病-2019 患者的性别差异

IF 1.5 Q3 PSYCHIATRY Middle East Current Psychiatry Pub Date : 2024-07-26 DOI:10.1186/s43045-024-00445-2
Rabab Maher, Hend Ibrahim Shousha, Nagwan Madbouly, Shimaa Afify, Suaad Sayed Moussa, Noha Asem, Amr Abdelazeem, Eslam Mohamed Youssif, Khalid Yousef Harhira, Hazem Elmorsy, Hassan Elgarem, Mohamed Hassany, Basem Eysa, Mohamed El-Kassas
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引用次数: 0

摘要

被称为COVID-19(2019年)大流行的冠状病毒疾病可能会增加出现心理症状的可能性,从而达到精神障碍的程度。我们旨在研究 COVID-19 患者在感染急性期和 6 个月后的精神疾病发病率,其中涉及性别差异和疾病严重程度。这是一项在 ClinicalTrials.gov (NCT04459403) 上注册的多中心随访研究。患者从埃及三家隔离医院连续招募。通过使用 Google Forms 制作的问卷收集数据,其中包括阿拉伯语版的一般健康问卷 (GHQ-12)、贝克抑郁量表 (BDI) 和泰勒显性焦虑量表 (TMAS)。6 个月后对抑郁、焦虑和创伤后应激障碍(PTSD)症状进行评估。研究向 400 名患者发放了调查问卷,199 名患者同意填写。轻度 COVID-19 患者的 BDI 和 TAMS 分别高于中度和重度 COVID-19 患者(分别为 14、8、8,P 值 = 0.009;17、13.5、14,P 值 = 0.04)。女性患抑郁症、焦虑症、睡眠问题和因焦虑而失眠的比例高于男性。教育程度、婚姻状况、既往精神病史和 COVID-19 的严重程度对抑郁有独立影响。婚姻状况、精神病家族史和慢性病对焦虑症有独立影响。在 6 个月的随访中,男性的 BDI 显著下降,而女性则没有。TMAS没有明显变化,但女性焦虑的严重程度仍然更高。创伤后应激障碍在女性中更为常见(分别为 26 例(37.1%)和 4 例(9.5%),P 值 = 0.02)。女性抑郁症和焦虑症的患病率和严重程度均高于男性,这表明女性受 COVID-19 大流行的影响更大。
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Gender differences in patients with corona virus disease-2019 presenting with psychiatric disturbances: a multicentre study
The coronavirus disease known as COVID-19 (2019) pandemic may increase the likelihood of psychological symptoms that can reach the level of psychiatric disorders. We aimed to study psychiatric morbidity in patients with COVID-19 concerning gender differences and disease severity in the acute phase of infection and after 6 months. This is a multicenter follow-up study registered in ClinicalTrials.gov (NCT04459403). Patients were recruited consecutively from three quarantine hospitals in Egypt. Data were collected through a questionnaire built using Google Forms including the Arabic versions of General Health Questionnaire (GHQ-12), Beck Depression Inventory (BDI), and Taylor Manifest Anxiety Scale (TMAS). Depression, anxiety, and post-traumatic stress disorder (PTSD) symptoms were assessed after 6 months. The study questionnaire was offered to 400 patients and 199 patients agreed to fill it. BDI and TAMS were higher in mild than moderate and severe COVID-19 (14, 8, 8, P-value = 0.009, 17, 13.5, 14, P-value = 0.04, respectively). Females showed a higher prevalence of depression, anxiety, sleep problems, and insomnia due to anxiety than males. Education level, marital status, previous psychiatric illness, and severity of COVID-19 independently affected depression. Marital status, family history of psychiatric illness, and chronic medical illness independently affected anxiety. On 6-month follow-up, BDI significantly decreased in males but not females. TMAS showed no significant changes, but the severity of anxiety was still higher in females. PTSD was more frequent in females (26 (37.1%) versus 4 (9.5%), respectively, P-value = 0.02). The prevalence and severity of depression and anxiety were higher in females than male participants, suggesting that females are more affected by the COVID-19 pandemic.
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来源期刊
Middle East Current Psychiatry
Middle East Current Psychiatry Medicine-Psychiatry and Mental Health
CiteScore
3.00
自引率
0.00%
发文量
89
审稿时长
9 weeks
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