前庭分裂瘤减压术中的回旋蛛网膜方法的疗效--对 60 例连续病例的回顾性队列研究。

Q3 Medicine Journal of Medicine and Life Pub Date : 2024-04-01 DOI:10.25122/jml-2024-0055
Hassan Kadri, Mohamad Shehadeh Agha, Raed Abouharb, Rostom Mackieh, Thea Kadri
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引用次数: 0

摘要

这项多中心回顾性队列研究旨在评估后枕部手术方法在前庭裂隙瘤减压中的有效性,重点关注肿瘤减压、神经功能保护和术后并发症。60 名患者于 2016 年至 2019 年期间接受了手术,研究人员采用既定标准对这些患者的年龄、性别、症状、肿瘤大小、手术时间、并发症、死亡率以及面部/听觉功能进行了分析。80%的患者出现听力损失,主要是进行性听力损失,肿瘤大小成为预后的关键因素。术前,10%的患者面部无力;术后,35%的患者面部神经功能受到影响,10%的患者面部神经功能较差或丧失,这与切除范围而非肿瘤大小有关。耳鸣在肿瘤较大时更为常见,而头痛则与肿瘤大小无关。术后平衡失调有所改善,尤其是较大的肿瘤。功能恢复情况各不相同,41.67%的患者在4个月内恢复到以前的活动状态,25%的患者在4-12个月内恢复,33.33%的患者仍处于非活动状态。死亡率较低,为 3.3%,60 名患者中有 2 人在手术后死亡。这项分析强调了前庭分裂瘤的手术风险(如面部神经衰退、耳鸣、头痛),但也强调了改善平衡和低死亡率等益处。许多患者恢复了职业活动,这强调了对这种疾病做出明智治疗决定的重要性。
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The outcome of the retrosigmoid approach in the decompression of vestibular schwannomas - a retrospective cohort study of 60 consecutive cases.

This multicenter retrospective cohort study aimed to evaluate the effectiveness of the retrosigmoid surgical approach in decompressing vestibular schwannomas, focusing on tumor decompression, neurological function preservation, and postoperative complications. A cohort of 60 patients, operated between 2016 and 2019, was analyzed for age, sex, symptoms, tumor size, surgery duration, complications, mortality, and facial/auditory functions using established criteria. Hearing loss was observed in 80% of patients, mainly progressive, with tumor size emerging as a critical prognostic factor. Facial weakness affected 10% of patients preoperatively; postoperatively, 35% of patients had affected facial nerve function, with 10% exhibiting poor or no facial nerve function, linked to resection extent rather than tumor size. Tinnitus was more prevalent with larger tumors, whereas headaches were common irrespective of size. Balance disorders improved after surgery, especially in case of larger tumors. Functional recovery varied, with 41.67% of patients returning to their previous activity within 4 months, 25% within 4-12 months, and 33.33% remaining inactive. The mortality rate was low at 3.3 %, with two deaths out of 60 patients after surgery. This analysis highlights surgery risks for vestibular schwannomas (e.g., facial nerve decline, tinnitus, headaches), but also emphasizes benefits like improved balance and low mortality. Many patients regain professional activity, stressing the importance of informed treatment decisions for this condition.

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来源期刊
Journal of Medicine and Life
Journal of Medicine and Life Medicine-Medicine (all)
CiteScore
1.90
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0.00%
发文量
202
期刊介绍: The Journal of Medicine and Life publishes peer-reviewed articles from various fields of medicine and life sciences, including original research, systematic reviews, special reports, case presentations, major medical breakthroughs and letters to the editor. The Journal focuses on current matters that lie at the intersection of biomedical science and clinical practice and strives to present this information to inform health care delivery and improve patient outcomes. Papers addressing topics such as neuroprotection, neurorehabilitation, neuroplasticity, and neuroregeneration are particularly encouraged, as part of the Journal''s continuous interest in neuroscience research. The Editorial Board of the Journal of Medicine and Life is open to consider manuscripts from all levels of research and areas of biological sciences, including fundamental, experimental or clinical research and matters of public health. As part of our pledge to promote an educational and community-building environment, our issues feature sections designated to informing our readers regarding exciting international congresses, teaching courses and relevant institutional-level events.
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