瓷主动脉和四重颅外血管闭塞:一例严重血管阻塞但神经功能缺损极小的病例。

IF 1 Q3 MEDICINE, GENERAL & INTERNAL American Journal of Case Reports Pub Date : 2024-07-29 DOI:10.12659/AJCR.944099
Reza Golchin Vafa, Nazanin Hosseini, Mohammad Montaseri, Javad Kojuri
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引用次数: 0

摘要

背景脑血管闭塞是与脑卒中相关的一个重要健康问题,也是全球死亡的主要原因。大血管闭塞在急性缺血性脑卒中中占很大比例,对患者造成严重后果。涉及多条颅外血管的闭塞非常罕见,但由于可能没有明显症状,给早期发现带来了挑战。病例报告 一位 65 岁的男性患者有明显的吸烟史,既往无高血压或心血管疾病史,因反复全身强直性发作而就诊,每天发作 4-5 次。尽管神经系统检查正常,但颈部超声检查显示颈动脉和椎动脉可能存在阻塞。常规血管造影显示冠状动脉有轻微斑块,但所有源自主动脉的颅内分支完全闭塞,并伴有瓷样主动脉。颈部 CT 血管造影证实主动脉上分支完全闭塞,右侧颈内动脉缺失,左侧颈内动脉近端闭塞。由于患者病情稳定,医生采取了内科治疗,没有进行外科手术。出院时,他接受了包括抗血小板治疗和他汀类药物在内的药物治疗。四个月的随访显示症状明显改善,CT 显示脑血流循环变化极小。结论 本病例强调了大脑在承受严重血管挑战方面的卓越适应能力。颅外多支血管闭塞的罕见情况和瓷主动脉的存在使病例更加复杂。利用先进的成像技术和个性化的治疗方法对于治疗复杂的血管疾病至关重要。持续的研究和仔细的监测对于促进对此类病例的理解和管理至关重要。
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Porcelain Aorta and Quadruple Extracranial Vessel Occlusion: A Case of Minimal Neurological Deficits Despite Severe Vascular Blockages.

BACKGROUND Cerebrovascular occlusion is a critical health concern associated with strokes, a leading cause of mortality worldwide. Large vessel occlusion, constituting a significant portion of acute ischemic strokes, presents serious patient outcomes. Occlusions involving multiple extracranial vessels are rare but pose challenges in early detection due to potential absence of overt symptoms. CASE REPORT A 65-year-old man with a significant smoking history and no prior history of hypertension or cardiovascular disease presented with recurrent generalized tonic seizures occurring 4 to 5 times daily. Despite normal neurological examinations, neck sonography indicated potential obstruction in the carotid and vertebral arteries. Conventional angiography revealed mild coronary artery plaques but complete occlusion of all cranial branches originating from the aorta, alongside porcelain aorta. Neck CT angiography confirmed complete occlusion of the supra-aortic branches of the aorta and absence of the right internal carotid artery, with evidence of proximal occlusion of the left internal carotid artery. Medical management without surgical intervention was pursued due to the patient's stable condition. He was discharged with a medication regimen including antiplatelet therapy and statins. Four-month follow-up showed significant symptom improvement, with minimal changes in brain blood flow circulation noted on CT. CONCLUSIONS This case underscores the brain's remarkable adaptive capacity in withstanding severe vascular challenges. The rarity of multiple extracranial vessel occlusions and presence of porcelain aorta further complicated the case. Utilizing advanced imaging techniques and personalized treatment approaches are crucial in managing complex vascular conditions. Ongoing research and careful monitoring are essential to advance understanding and management in such cases.

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来源期刊
American Journal of Case Reports
American Journal of Case Reports Medicine-Medicine (all)
CiteScore
1.80
自引率
0.00%
发文量
599
期刊介绍: American Journal of Case Reports is an international, peer-reviewed scientific journal that publishes single and series case reports in all medical fields. American Journal of Case Reports is issued on a continuous basis as a primary electronic journal. Print copies of a single article or a set of articles can be ordered on demand.
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