非临床样本中的童年创伤、心智化和强迫症症状:中介分析研究

IF 2 Q3 CLINICAL NEUROLOGY Clinical Neuropsychiatry Pub Date : 2024-06-01 DOI:10.36131/cnfioritieditore20240305
Elena De Rossi, Claudio Imperatori, Francesco Sciancalepore, Elisabeth Prevete, Annalisa Maraone, Marco Canevelli, Lorenzo Tarsitani, Massimo Pasquini, Benedetto Farina, Francesco Saverio Bersani
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引用次数: 0

摘要

目的:强迫症(OCS)是一种跨领域的精神病理学表现,经常在各种临床和非临床样本中发现。有研究认为,儿童时期的思维能力受损和创伤经历可能是 OCS 的相关致病因素。本研究的目的是在非临床样本中对这些变量进行横截面评估,测试思维能力在童年创伤(CT)和 OCS 之间的关联中的中介作用:667名参与者(488名女性;平均年龄= 29.76 ± 11.87岁;年龄范围:18-80岁)回答了包括童年创伤问卷、心智化问卷和简易症状量表强迫分量表在内的调查:中介模型的总效果显著(p< .001),表明 CT 与 OCS 呈正相关(95% CI:.006; .019),而这种相关性是由心智化能力的降低水平中介的(95% CI:.003; .009)。在控制了潜在的社会人口学和临床混杂变量后,上述结果具有重要意义:研究结果有助于阐明CT、心智能力和OCS之间的复杂关系,支持CT导致的心智障碍可能会影响自上而下的控制机制,从而导致OCS的发生。
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Childhood Trauma, Mentalization and Obsessive Compulsive Symptoms in a Non-Clinical Sample: A Mediation Analysis Study.

Objective: Obsessive and compulsive symptoms (OCS) are cross-cutting psychopathological manifestations frequently detected in a variety of clinical and non-clinical samples. It has been suggested that impaired mentalization abilities and traumatic experiences during childhood may be relevant etiopathogenetic factors in the development of OCS. The purpose of the current study was to cross-sectionally assess these variables in a non-clinical sample, testing the mediational role of mentalization abilities in the association between childhood trauma (CT) and OCS.

Method: 667 participants (488 females; mean age= 29.76 ± 11.87 years; age range: 18-80) answered a survey including the Childhood Trauma Questionnaire, the Mentalization Questionnaire and the Obsession-Compulsion subscale of the Brief Symptom Inventory.

Results: The mediation model was significant for the total effect (p< .001), showing that CT was positively associated with OCS (95% CI: .006; .019) and that this association was mediated by reduced levels of mentalization capacity (95% CI: .003; .009). Such results were significant controlling for potential sociodemographic and clinical confounding variables.

Conclusions: The findings contribute to elucidate the complex relationships between CT, mentalization capacity, and OCS, supporting the possibility that mentalization impairments, arising from CT, may affect top-down control mechanisms thus contributing to the development of OCS.

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来源期刊
Clinical Neuropsychiatry
Clinical Neuropsychiatry CLINICAL NEUROLOGY-
CiteScore
11.10
自引率
1.60%
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0
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