Yiting Liu, Rongfei Yang, Nana Zhang, Qingshan Liu
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引用次数: 0
摘要
目的：抑郁症是一个重大的公共卫生问题。许多补充和替代医学（CAM）干预措施被建议作为潜在的治疗方法：我们在 PubMed、EMBASE、Web of Science 和 Cochrane Library 数据库中全面检索了相关的系统综述和荟萃分析。我们根据效率和抑郁评估量表评分的变化来评估有效性，并根据不良事件来评估安全性：本综述共纳入了 22 篇符合条件的文章。越剧抗抑郁药和电针（EA）对抑郁症状的改善效果优于抗抑郁药。此外，ω-3 脂肪酸（n-3PUFAs）、运动、手工针灸（MA）、金丝桃单方制剂、放松和维生素 D 的疗效优于安慰剂和对照组。GPD作为辅助疗法的有效率高于抗抑郁药，而MA和越剧抗抑郁药的安全性优于抗抑郁药：我们的研究表明，10 种 CAMs 可有效改善临床抑郁症患者的病情。
The Efficacy and Safety of Complementary and Alternative Medicine for Depression: An Umbrella Review.
Objective: Depression is a major public health problem. Many complementary and alternative medicine (CAM) interventions have been suggested as potential treatments.
Methods: We comprehensively searched for relevant systematic reviews and meta-analyses in the PubMed, EMBASE, Web of Science, and Cochrane Library databases. We assessed effectiveness based on efficiency and changes in Depression Assessment Scale scores and safety based on adverse events.
Results: This umbrella review included twenty-two eligible articles. Yueju antidepressant and Electro-acupuncture (EA) improved depression symptoms better than antidepressants. In addition, omega-3 fatty acids (n-3PUFAs), exercise, manual acupuncture (MA), Hypericum mono-preparations, relaxation, and Vitamin D showed better efficacy than placebo and control. GPD as adjunctive therapies have higher efficacy rates than antidepressant, and MA and Yueju antidepressants have a better safety profile than antidepressants.
Conclusion: Our study demonstrated that 10 CAMs can effectively improve the condition of patients with clinical depression.
期刊介绍：
The Revista Brasileira de Psiquiatria (RBP) is the official organ of the Associação Brasileira de Psiquiatria (ABP - Brazilian Association of Psychiatry).
The Brazilian Journal of Psychiatry is a bimonthly publication that aims to publish original manuscripts in all areas of psychiatry, including public health, clinical epidemiology, basic science, and mental health problems. The journal is fully open access, and there are no article processing or publication fees. Articles must be written in English.
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