{"title":"解开烯二炔生物合成之谜","authors":"Max B. Sosa, Michelle C. Y. Chang","doi":"10.1038/s41589-024-01686-2","DOIUrl":null,"url":null,"abstract":"The biosynthetic intermediate of the common core of enediyne natural products has been enigmatic for decades. Now, researchers report the identification of a diiodotetrayne compound as the universal enediyne biosynthetic intermediate.","PeriodicalId":18832,"journal":{"name":"Nature chemical biology","volume":null,"pages":null},"PeriodicalIF":12.9000,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Solving the mystery of enediyne biosynthesis\",\"authors\":\"Max B. Sosa, Michelle C. Y. Chang\",\"doi\":\"10.1038/s41589-024-01686-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The biosynthetic intermediate of the common core of enediyne natural products has been enigmatic for decades. Now, researchers report the identification of a diiodotetrayne compound as the universal enediyne biosynthetic intermediate.\",\"PeriodicalId\":18832,\"journal\":{\"name\":\"Nature chemical biology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":12.9000,\"publicationDate\":\"2024-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature chemical biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.nature.com/articles/s41589-024-01686-2\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature chemical biology","FirstCategoryId":"99","ListUrlMain":"https://www.nature.com/articles/s41589-024-01686-2","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
The biosynthetic intermediate of the common core of enediyne natural products has been enigmatic for decades. Now, researchers report the identification of a diiodotetrayne compound as the universal enediyne biosynthetic intermediate.
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Nature Chemical Biology stands as an esteemed international monthly journal, offering a prominent platform for the chemical biology community to showcase top-tier original research and commentary. Operating at the crossroads of chemistry, biology, and related disciplines, chemical biology utilizes scientific ideas and approaches to comprehend and manipulate biological systems with molecular precision.
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