构建阿哌沙班类似物的另一种合成策略

IF 0.8 4区化学 Q4 CHEMISTRY, ORGANIC Arkivoc Pub Date : 2024-07-27 DOI:10.24820/ark.5550190.p012.151

R. Dandela, Dattatray Gaikwad, Rana Chatterjee, Sujeet A. Gaware, Achyuta Nanda Acharya

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引用次数: 0

摘要

已经介绍了一种获得新型阿哌沙班类似物的替代合成方法。本策略提供了一种实用且具有成本效益的合成程序，可用于构建特异性支架及其酰胺衍生物，这些衍生物可能会表现出良好的抗凝效力。此外，该方法还使用了价格较低的试剂、易于实现的前体

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An alternative synthetic strategy to construct apixaban analogues

An alternate synthetic approach has been described to access novel apixaban analogues. The present strategy offers a practical and cost-effective synthetic procedure to construct the privileged scaffold and its amide derivatives that may exhibit promising anticoagulant potency. Moreover, the method was performed by using less expensive reagents, easily achievable precursors

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来源期刊

Arkivoc 化学-有机化学

CiteScore

1.10

自引率

11.10%

发文量

120

审稿时长

3.1 months

期刊介绍： Arkivoc publishes full papers (not accounts) describing sound original work that is of interest to organic chemists (in areas of synthetic organic chemistry, bio-organic, organometallic, theoretical, and physical organic chemistry: General Papers describing sound original work Reviews and Accounts of selected topics Honorary Issues - Pay tribute to distinguished organic chemists (invited contributions) Thematic Issues - Cover important current topics in organic chemistry Regional Issues - Recognize organic chemistry in various countries.