开发治疗口腔疾病的功能性水凝胶

Chuanhui Song, Rui Liu, Yile Fang, Hongcheng Gu, Yu Wang
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引用次数: 0

摘要

口腔疾病是一项严峻的医疗挑战,会降低人们的生活质量。具有适当生物降解性、生物相容性和可调机械特性的功能性水凝胶引起了人们的极大兴趣,并已被开发用于治疗口腔疾病。在这篇综述中,我们将根据牙科疾病的进展情况,介绍水凝胶用于治疗龋齿、牙髓病、根尖周炎和牙周炎的最新研究成果。然后对水凝胶治疗口腔黏膜疾病和唾液腺疾病的策略进行了分类。之后,我们重点讨论了水凝胶在肿瘤治疗和组织缺损方面的应用。最后,综述展望了水凝胶用于口腔疾病治疗的限制和前景。我们相信,这篇综述将促进口腔疾病治疗方法更加友好、功能化和个性化。
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Developing functional hydrogels for treatment of oral diseases
Oral disease is a severe healthcare challenge that diminishes people's quality of life. Functional hydrogels with suitable biodegradability, biocompatibility, and tunable mechanical properties have attracted remarkable interest and have been developed for treating oral diseases. In this review, we present up‐to‐date research on hydrogels for the management of dental caries, endodontics, periapical periodontitis, and periodontitis, depending on the progression of dental diseases. The strategies of hydrogels for treating oral mucosal diseases and salivary gland diseases are then classified. After that, we focus on the application of hydrogels related to tumor therapy and tissue defects. Finally, the review prospects the restrictions and the perspectives on the utilization of hydrogels in oral disease treatment. We believe this review will promote the advancement of more amicable, functional and personalized approaches for oral diseases.
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