男性雄激素性脱发患者口服小剂量米诺地尔的副作用频率评估

IF 1.4 Q3 DERMATOLOGY Skin Appendage Disorders Pub Date : 2024-07-23 DOI:10.1159/000539969
Leila David Bloch, Rafaelly Mayara Dantas Carlos
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引用次数: 0

摘要

简介:脱发是皮肤科医生诊室中非常常见的主诉病症,需要使用经证实安全有效的疗法来改善脱发状况,同时又不损害患者的健康和福祉。治疗方法我们挑选了 100 名男性雄激素性脱发患者,开始使用小剂量口服米诺地尔治疗,观察副作用的发生率和频率。结果在接受评估的患者中观察到的副作用/症状包括身体和面部多毛(最多)、小腿水肿、眶周水肿、疲劳、心动过速和失眠。预计会出现头晕、低血压、呼吸系统变化和腹泻,但未在接受评估的参与者中发现。没有观察到危及生命的不良反应。结论在目前的研究中,口服米诺地尔作为脱发治疗药物的剂量具有良好的安全性,最常见的副作用与多毛症有关。全身性副作用并不常见。
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Side Effects’ Frequency Assessment of Low Dose Oral Minoxidil in Male Androgenetic Alopecia Patients
Introduction: Hair loss is a very common complaint in dermatologists’ offices, requiring the use of proven safe and effective therapies to improve the condition without jeopardizing patients’ health and well-being. Methods: We selected 100 male patients with androgenetic alopecia beginning treatment with low dose oral minoxidil to observe incidence and frequency of side effects. Results: The side-effects/symptoms observed in the assessed patients included body and facial hypertrichosis (most incidents), lower legs edema, periorbital edema, fatigue, tachycardia, and insomnia. Dizziness, hypotension, respiratory changes, and diarrhea were expected although not found in the assessed participants. No life-threatening adverse effects were observed. Conclusion: The doses administered in current research of oral minoxidil presented good safety profile as hair loss treatment, with the most incident side-effect being related to hypertrichosis. Systemic side-effects were infrequent.
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来源期刊
CiteScore
2.00
自引率
10.00%
发文量
69
期刊最新文献
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