采用分期手术切除和永久性切口面上处理技术复查白斑病的肿瘤边缘

Michael Adkison, Andrew Armenta, Frank T. Winsett, Richard F Wagner
{"title":"采用分期手术切除和永久性切口面上处理技术复查白斑病的肿瘤边缘","authors":"Michael Adkison, Andrew Armenta, Frank T. Winsett, Richard F Wagner","doi":"10.25251/skin.8.4.5","DOIUrl":null,"url":null,"abstract":"Background: The optimal surgical margins required for the excision of lentigo maligna remains a topic of debate. Recent literature suggests that wider margins are warranted. \nObjective: Comparison of lentigo maligna margin sizes and clearance rates from a single center to existing literature. \nMethods: A retrospective analysis of primary and recurrent lentigo maligna treated by staged excision with complete circumferential and deep margin assessment between 2011 and 2023 at a single institution was conducted. The percentage of tumors with clear margins after the initial excision with 5 mm margins was determined. \nResults: A total of 65 tumors were identified. Fifty-eight patients (89.2%) had clear margins after initial excision with 5 mm margins.  \nConclusions: This study reports a higher percentage of lentigo maligna clearance following the initial staged excision with 5 mm margins than reports in the literature. These differences may be attributed to variations in section processing, staining techniques, and factors associated with differences in subclinical spread.","PeriodicalId":22013,"journal":{"name":"SKIN The Journal of Cutaneous Medicine","volume":"29 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Review of Tumor Margins for Lentigo Maligna with Staged Surgical Excision and Permanent Section en face Processing\",\"authors\":\"Michael Adkison, Andrew Armenta, Frank T. Winsett, Richard F Wagner\",\"doi\":\"10.25251/skin.8.4.5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: The optimal surgical margins required for the excision of lentigo maligna remains a topic of debate. Recent literature suggests that wider margins are warranted. \\nObjective: Comparison of lentigo maligna margin sizes and clearance rates from a single center to existing literature. \\nMethods: A retrospective analysis of primary and recurrent lentigo maligna treated by staged excision with complete circumferential and deep margin assessment between 2011 and 2023 at a single institution was conducted. The percentage of tumors with clear margins after the initial excision with 5 mm margins was determined. \\nResults: A total of 65 tumors were identified. Fifty-eight patients (89.2%) had clear margins after initial excision with 5 mm margins.  \\nConclusions: This study reports a higher percentage of lentigo maligna clearance following the initial staged excision with 5 mm margins than reports in the literature. These differences may be attributed to variations in section processing, staining techniques, and factors associated with differences in subclinical spread.\",\"PeriodicalId\":22013,\"journal\":{\"name\":\"SKIN The Journal of Cutaneous Medicine\",\"volume\":\"29 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"SKIN The Journal of Cutaneous Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25251/skin.8.4.5\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"SKIN The Journal of Cutaneous Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25251/skin.8.4.5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:切除白斑所需的最佳手术切缘仍是一个争论不休的话题。最近的文献表明,需要更宽的边缘。目的:比较不同中心的白斑病切除边缘:将单个中心的白斑边缘大小和清除率与现有文献进行比较。方法:对 2011 年至 2023 年间在一家机构接受分期切除术治疗的原发性和复发性恶性扁平苔藓进行回顾性分析,并进行完整的周缘和深缘评估。确定了初次切除 5 毫米边缘后边缘清晰的肿瘤比例。结果:共发现 65 例肿瘤。58例患者(89.2%)在初次切除5毫米边缘后边缘清晰。 结论:该研究报告了较高比例的大叶肿瘤:与文献报道相比,本研究报告了初始分期切除 5 毫米边缘的恶性肿瘤清除率。这些差异可能是由于切片处理、染色技术以及亚临床扩散差异相关因素造成的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Review of Tumor Margins for Lentigo Maligna with Staged Surgical Excision and Permanent Section en face Processing
Background: The optimal surgical margins required for the excision of lentigo maligna remains a topic of debate. Recent literature suggests that wider margins are warranted. Objective: Comparison of lentigo maligna margin sizes and clearance rates from a single center to existing literature. Methods: A retrospective analysis of primary and recurrent lentigo maligna treated by staged excision with complete circumferential and deep margin assessment between 2011 and 2023 at a single institution was conducted. The percentage of tumors with clear margins after the initial excision with 5 mm margins was determined. Results: A total of 65 tumors were identified. Fifty-eight patients (89.2%) had clear margins after initial excision with 5 mm margins.  Conclusions: This study reports a higher percentage of lentigo maligna clearance following the initial staged excision with 5 mm margins than reports in the literature. These differences may be attributed to variations in section processing, staining techniques, and factors associated with differences in subclinical spread.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Off-Label Uses of Upadacitinib Stability of Long-Term Therapeutic Responses to Tralokinumab in Adults with Moderate-to-Severe Atopic Dermatitis What Do Clinicians Mean When Submitting a Biopsy as “Rule Out Eczema” Deucravacitinib in Plaque Psoriasis: Maintenance of Response Over 4 Years in the Phase 3 POETYK PSO-1, PSO-2, and LTE Trials Zosteriform Atrophoderma of Pasini and Pierini: A Case Report
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1