采用分期手术切除和永久性切口面上处理技术复查白斑病的肿瘤边缘

Michael Adkison, Andrew Armenta, Frank T. Winsett, Richard F Wagner
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引用次数: 0

摘要

背景:切除白斑所需的最佳手术切缘仍是一个争论不休的话题。最近的文献表明,需要更宽的边缘。目的:比较不同中心的白斑病切除边缘:将单个中心的白斑边缘大小和清除率与现有文献进行比较。方法:对 2011 年至 2023 年间在一家机构接受分期切除术治疗的原发性和复发性恶性扁平苔藓进行回顾性分析,并进行完整的周缘和深缘评估。确定了初次切除 5 毫米边缘后边缘清晰的肿瘤比例。结果:共发现 65 例肿瘤。58例患者(89.2%)在初次切除5毫米边缘后边缘清晰。 结论:该研究报告了较高比例的大叶肿瘤:与文献报道相比,本研究报告了初始分期切除 5 毫米边缘的恶性肿瘤清除率。这些差异可能是由于切片处理、染色技术以及亚临床扩散差异相关因素造成的。
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Review of Tumor Margins for Lentigo Maligna with Staged Surgical Excision and Permanent Section en face Processing
Background: The optimal surgical margins required for the excision of lentigo maligna remains a topic of debate. Recent literature suggests that wider margins are warranted. Objective: Comparison of lentigo maligna margin sizes and clearance rates from a single center to existing literature. Methods: A retrospective analysis of primary and recurrent lentigo maligna treated by staged excision with complete circumferential and deep margin assessment between 2011 and 2023 at a single institution was conducted. The percentage of tumors with clear margins after the initial excision with 5 mm margins was determined. Results: A total of 65 tumors were identified. Fifty-eight patients (89.2%) had clear margins after initial excision with 5 mm margins.  Conclusions: This study reports a higher percentage of lentigo maligna clearance following the initial staged excision with 5 mm margins than reports in the literature. These differences may be attributed to variations in section processing, staining techniques, and factors associated with differences in subclinical spread.
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