Dimitris Rigopoulos, A. Tsiogka, Dimitrios Malanos, S. Gregoriou
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Background: Nail involvement is very frequent in psoriasis and may significantly affect patients’ quality of life due to clinical and functional impairment. In addition, nail psoriasis constitutes a negative prognostic factor for the development of psoriatic arthritis (PsA), even in the absence of cutaneous disease. Summary: Herein we provide an updated review on the diagnostic evaluation of nail psoriasis using clinical assessment and implementation of imaging techniques including dermoscopy, capillaroscopy, ultrasonography, and optical coherence tomography. In addition, we summarize consensus guidelines for the management of nail psoriasis and provide efficacy data on the use of intralesional, topical, and the most recently approved targeted systemic therapies. Key Messages: Physicians should be aware of the importance of prompt diagnosis and management of nail psoriasis, to improve patient outcomes and decrease the risk of PsA development.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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