Ahmed M. Amshawee, Maryam A. Hussain, Seenaa Taqi Mansour Al Muhtaser, Ali A. Al- Faham
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引用次数: 0
摘要
脱氧核糖核酸（DNA）携带遗传密码，细胞将其翻译成核糖核酸（RNA）和多肽，从而产生并执行重要功能。双螺旋结构是研究最多的 DNA 模型，由沃森和克里克提出。DNA 作为遗传物质的能力可以在细胞分裂过程中储存和传导，以便将信息加倍并传递给下一代。DNA 结构的任何损伤都是导致癌症和其他疾病恶化的重要直接原因。造成 DNA 损伤的因素可分为外源性因素和内源性因素。在这篇综述文章中，我们将重点介绍有关 DNA 结构、功能和临床意义的证据支持信息。
Structure, Functions And Clinical Significance Of DNA: A Review Article
The deoxyribonucleic acid (DNA) carries hereditary codes which is translated by the cells to synthesize the ribonucleic acid (RNA) and polypeptides which can generate and perform vital function. The double helix structure is the most studied model of the DNA that was proposed by Watson and Crick. The capability of DNA to work as a genetic material can be stored and conducted during cell division to permit this information to be doubled and transmitted to the incoming generation. Any damage in the structure of DNA is an essential direct cause for the progression of cancer and other disorders. The factors for DNA damage can be classified as exogenous and endogenous factors. In this review article, we highlight the evidence-supported information about the structure, functions and clinical significance of DNA.
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