外用初榨椰子油对预防妊娠纹和妊娠纹严重程度的影响:随机对照试验

Rahmatul Ulya, Sunesni, Yohana Suganda, Mekar Zenni Radhia, Eureka Herba
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引用次数: 0

摘要

妊娠纹(SG),俗称妊娠斑,是孕期常见的问题。初榨椰子油(VCO)传统上用于皮肤保健,可能具有预防妊娠纹的潜力。这项随机对照试验(RCT)旨在评估外用初榨椰子油对预防和减轻印度尼西亚克林齐地区孕妇妊娠纹严重程度的功效。怀孕后三个月的孕妇(人数=200)被随机分配接受外用 VCO 或安慰剂(标准润肤剂)治疗,每天两次。在基线、妊娠 32 周和产后六周时,使用改良的妊娠纹评估量表(SGAS)对 SG 的严重程度进行评估。与安慰剂相比,使用 VCO 可显著降低新 SG 的发生率(25% 对 45%,P < 0.05)。此外,在 32 周和产后,VCO 组的 SG 严重程度明显降低(SGAS 平均分:VCO 1.8 vs. 安慰剂:VCO 1.8 vs. 安慰剂:VCO 1.8 vs. VCO 1.8):32周时,VCO为1.8分,安慰剂为2.6分,P<0.05;产后时,VCO为1.4分,安慰剂为2.2分,P<0.01)。无不良反应报告。总之,外用 VCO 对于预防孕期新的 SG 和减轻现有 SG 的严重程度似乎是安全有效的。还需要进一步研究其潜在机制和长期效果。
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The Effect of Topical Virgin Coconut Oil on Striae Gravidarum Prevention and Severity: A Randomized Controlled Trial
Striae gravidarum (SG), commonly known as stretch marks, is a common concern during pregnancy. Virgin coconut oil (VCO) is traditionally used for skin health and may have potential in SG prevention. This randomized controlled trial (RCT) aimed to assess the efficacy of topical VCO in preventing and reducing the severity of SG among pregnant women in Kerinci Regency, Indonesia. Pregnant women (n=200) in their second trimester were randomized to receive either topical VCO or a placebo (standard emollient) twice daily. SG severity was assessed using a modified striae gravidarum assessment scale (SGAS) at baseline, 32 weeks gestation, and six weeks postpartum. VCO application was associated with a significantly lower incidence of new SG compared to the placebo (25% vs. 45%, p < 0.05). Furthermore, the VCO group showed a significant reduction in SG severity at 32 weeks and postpartum (mean SGAS scores: VCO 1.8 vs. placebo 2.6 at 32 weeks, p < 0.05; VCO 1.4 vs. placebo 2.2 at postpartum, p < 0.01). No adverse effects were reported. In conclusion, topical VCO appears to be safe and effective in preventing new SG and reducing the severity of existing SG during pregnancy. Further research is warranted to explore the underlying mechanisms and long-term effects.
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