痤疮患者瘙痒发生率分析及其特点

A. Lvov, E. E. Sidorenko, O. A. Sidorenko
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摘要

导言。痤疮是一种由多种因素引起的皮脂腺毛囊慢性炎症性疾病,表现为开放性和闭合性粉刺、丘疹、脓疱和结节。研究痤疮患者的瘙痒发生率,并评估其对患者生活质量和心理情绪的影响。观察对象为 249 名确诊为痤疮的患者,年龄在 12 至 50 岁之间,其中女性 143 名(57.4%),男性 106 名(42.6%)。根据患者的主诉、病史和临床表现对其进行诊断。为了评估瘙痒对生活质量的影响,研究人员使用了痤疮心理和社会影响量表(APSEA)、皮肤病生活质量指数(DLQI)、卡迪夫社会适应指数(CADI)、罗森伯格自尊量表和一份自制的调查问卷来评估瘙痒对生活质量的影响。问卷、《OUR itch.Results》。为了解决这些问题,根据纳入、未纳入和排除标准,组成了两组在主要临床诊断指标方面具有可比性的临床对比组。第一组由痤疮引起瘙痒的患者组成(64 人,占受试者的 26%),第二组由无瘙痒的患者组成(185 人,占受试者的 74%)。研究结果显示,痤疮瘙痒与年龄、性别、是否肥胖、碳水化合物耐受性受损、缺铁性贫血、高泌乳素血症之间存在统计学意义上的显著关系,描述了受试者瘙痒的各种特征,并揭示了所用指数指标之间的密切联系。研究痤疮中瘙痒的发生率是一个相关领域,它使我们能够扩大对主观感觉在痤疮发展中的作用的认识,并进一步评估这种皮肤病对患者生活质量的影响。
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Itch prevalence analysis and its characteristics among acne patients
Introduction. Acne is a multifactorial chronic inflammatory disease of the pilosebaceous follicle, which manifests itself as open and closed comedones, papules, pustules and nodules.Purpose of the study. Studying of itch prevalence among patients with acne, as well as assessing its impact on their quality of life and psychoemotional status.Materials and methods. Under observation were 249 patients diagnosed with acne aged from 12 to 50 years, of which 143 women (57.4%), 106 men (42.6%). Patients were diagnosed based on complaints, anamnesis and clinical picture of the disease. To assess the impact of itching on the quality of life, the Acne Psychological and Social Effect Scale (APSEA), the Dermatological Life Quality Index (DLQI), the Cardiff Social Disadaptation Index (CADI), the Rosenberg self-esteem scale, and a self-developed questionnaire were used to assess the impact of itching on the quality of life. Questionnaire, YOUR itch.Results. To solve these problems, based on the criteria for inclusion, non-inclusion and exclusion, two clinical comparison groups were formed, comparable in terms of main clinical diagnostic indicators. The first group consisted of patients with itching due to acne (64 people, 26% of subjects), the second group consisted of patients with no itching (185 people, 74% of subjects). According to the results of the study, a statistically significant relationship between the presence of itching in acne and age, gender, the presence of obesity, impaired carbohydrate tolerance, iron deficiency anemia, hyperprolactinemia was revealed, various characteristics of itching in the subjects were described, and a close correlation of the indicators of the indices used was revealed.Conclusions. Studying the prevalence of itching in acne is a relevant area and allows us to expand our understanding of the role of subjective sensations in the development of acne and further evaluate the impact of this dermatosis on the quality of life of patients.
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