评估斑秃严重程度的现代方法的有效性

E. Matushevskaya
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摘要

研究目的评估标准化 SALT 量表在确定 AA 患者病情严重程度方面的有效性。进行一次性回顾性队列研究。共有 40 名接受监护的 AA 患者。患者的性别分布如下:男性 15 人(36.6%),女性 25 人(63.3%)。平均年龄为 29.4 岁,介于 18-54 岁之间。初次登台的 AA 患者年龄差异很大,从 2 岁到 45 岁不等。病理过程开始的平均年龄为 18.2±4.4 岁。22.4%的患者头皮毛发面积超过 25%,身体其他部位也出现脱发和指甲变化。54.5%的头皮毛发病变面积超过 25%的患者会出现两次以上的复发,只有 9.2%的患者会出现胎儿型 AA。根据 SBN 脱发状况量表,S1 临床上与局灶性脱发相对应,S2 -S4 - 卵巢性脱发、多灶性脱发,S5 - TA 和 UA。临床表现为 S2-S3 和 S4-S5 的患者中,分别有 38% 和 67% 在这些部位出现部分或全部脱发。在接受检查的 AA 患者中,有 25% 的病例合并有不同程度的体毛脱落和甲板萎缩。在确定脱发严重程度时,主要不仅要看头皮皮损的大小和数量,还要看眉毛和睫毛皮肤脱发的性质,以及脱发和甲板萎缩性改变的可能组合,这被认为是病程更严重的一种选择。SBN 系统根据标准化量表有效地评估和描述了 AA 的临床变异,有助于确定不同表现患者的临床治疗方法,并预测疾病的进程。
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Efficacy of modern methods for assessing the severity of alopecia areata
Purpose of the study. To evaluate the effectiveness of the standardized SALT scale to determine the severity of AA patients.Materials and methods. A one-time retrospective cohort study was conducted. There were 40 patients with AA under supervision. The gender distribution of the patients was as follows: 15 men (36.6%) and 25 (63.3%) women. The average age was 29.4 years in the 18–54 age range.Results. The AA debut varied widely in age range from 2 to 45 years. The average age at which the pathological process began was 18,2±4,4 years. 22.4% of patients with a scalp hair area of more than 25%, as well as hair loss in other areas of the body and changes in the nail.The beginning of AA is fixed to 10 years. More than two relapses occurred in 54.5% of patients with scalp hair lesions of more than 25% and only 9.2% of cases with foetal AA.The following clinical forms were diagnosed: foetal (12 patients), lenticular (ophiasis, inversive ophiasis) (7 patients), multi-focal (11 patients), total and universal (10 patients). According to the SBN Hair Loss State scale, S1 clinically corresponded to focal alopecia, S2 -S4 – ophazis, multi-focal alopecia, S5 – TA and UA. Partial or complete hair loss has been noted in these areas in 38% of patients with S2-S3 and 67% with S4-S5 clinical forms. The combination of different degrees of body hair loss and dystrophy of nail plates in examined AA patients was observed in 25% of cases.Conclusion. In determining the severity of alopecia nest principally not only the size and number of lesions on the skin scalp, but also the nature of hair loss on the skin of the eyebrows and eyelashes, as well as the possible combination of hair loss and dystrophic altered nail plates, which is considered an option for a more severe course of the disease. The SBN system effectively evaluates and describes the clinical variant of AA according to a standardized scale, which can help determine clinical management of patients with different manifestations, as well as predict the course of the disease.
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