关于抑郁与脑卒中患者残疾程度相关性的研究

Roshna Balakrishnan, B. K. H.
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摘要

背景:中风是一种急症,可造成永久性神经损伤、并发症甚至死亡。抑郁障碍和功能减退已被认为是脑卒中的常见后果。超过一半的脑卒中幸存者会留下残疾,无法恢复到卒中前的健康水平和工作能力。脑卒中后抑郁被认为是脑卒中最常见、最重要的神经-精神后果。由于中风后会出现抑郁障碍和残疾,本研究的目的是找出中风患者抑郁与残疾程度之间的相关性。抑郁程度采用汉密尔顿抑郁量表(Hamilton Depression Rating Scale,HDRS)进行测量,评分范围为 0 至 54 分;残疾程度采用修正的兰金量表(modified Rankin Scale,mRS)进行测量,评分范围为 0 至 6 分。抑郁采用汉密尔顿抑郁量表(HDRS)进行测量。统计分析:- 卡尔-皮尔逊相关性- P 值<0.05 为统计学显著性结果:r 值为 0.836,P 值为 0.000,结果具有高度显著性,P<0.05 为显著性。由于它是一个正值(0.836),我们可以得出结论,中风患者的抑郁(HDRS)与残疾程度(mRS)之间存在显著的正相关:卒中、抑郁、残疾、汉密尔顿抑郁评定量表(HDRS)、改良Rankin量表(mRS)。
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A Study to Find Out Correlation of Depression with The Level of Disability in Stroke Patients
BACKGROUND: Stroke is a medical emergency, and can cause permanent neurological damage, complications, and even death. Depressive disorders and diminished functional capabilities have been recognized as common consequences of stroke More than one half of all stroke survivors are left with disabilities that prevent them from returning to their prestroke level of health and productivity. Poststroke depression is considered as the most frequent and important neuro-psychiatric consequence of stroke. As both depressive disorders and disability occurs after stroke, the purpose of the study is to correlate and find the relationship of depression with the level of disability in stroke patients. METHOD: A total of 100 stroke patients of both sexes in the age group of 30 to 60 years within a given time duration of 6 months after stroke were assessed for their depression and disability level. Depression was measured using Hamilton Depression Rating Scale (HDRS) with scores ranging from 0 to 54 and Disability was measured using modified Rankin Scale (mRS) with scores ranging from 0 to 6. OUTCOME MEASURE: The following outcome measures were measured: 1. Depression was measured using Hamilton Depression Rating Scale (HDRS) 2. Disability was measured using modified Rankin Scale (mRS) STATISTICAL ANALYSIS: • Karl Pearson’s correlation • P value <0.05 is taken up for statistical significance RESULTS: The r- value is 0.836, p- value is 0.000 and the result is highly significant with p<0.05 significance. In this study, r is between -1 and 1. Since it is a positive value (0.836), we can conclude that there exist a significant positive correlation between depression (HDRS) and level of disability (mRS) in stroke patients. CONCLUSION: Depression had a strong positive correlation with Disability in stroke patients Keywords: Stroke, Depression, Disability, Hamilton Depression Rating Scale (HDRS), Modified Rankin Scale (mRS).
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