彻底改变医疗保健和药物发现:人工智能对药物开发的影响

IF 0.3 Q4 PHARMACOLOGY & PHARMACY Current Drug Therapy Pub Date : 2024-07-19 DOI:10.2174/0115748855313948240711043701
Kumaran Chinnaiyan, Sruthi Laakshmi Mugundhan, Damodharan Narayanasamy, Mothilal Mohan
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引用次数: 0

摘要

人工智能(AI)正在重塑制药业的药物发现和交付,从根本上改变传统方法。在药物发现方面,人工智能算法可快速分析庞大的生物和化学数据集,以前所未有的准确性识别潜在的候选药物。机器学习模型可预测化合物的疗效和安全性,从而加速早期药物开发。人工智能还有助于药物的再利用,发掘现有药物的新治疗用途。在给药方面,人工智能优化了配方和系统,实现了靶向和个性化给药。智能算法增强了对药代动力学和药效学的理解,为精准医疗战略的制定提供了指导。人工智能的这种整合不仅加快了创新药物的发现,还完善了给药机制,有望提供更有效、更量身定制的治疗,并有可能彻底改变患者护理。人工智能的数据处理能力推动了数字化和广泛应用。在药物发现、开发、再利用和临床试验中的应用旨在减轻人类工作量,加快目标实现,促进创新。尽管前景广阔,但在实施人工智能的同时,人们也担心工作岗位的流失和严格的法规。业内人士强调,人工智能的目的是增强人类的劳动能力,而不是完全取代人类,他们预计人工智能将成为一种关键资源,推动医疗保健领域的效率、创新和进步。本综述强调了人工智能在改变药物发现和交付方面的作用
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Revolutionizing Healthcare and Drug Discovery: The Impact of Artificial Intelligence on Pharmaceutical Development
Artificial intelligence (AI) is reshaping drug discovery and delivery in the pharmaceutical industry, fundamentally transforming traditional methods. In drug discovery, AI algorithms rapidly analyze vast biological and chemical datasets to identify potential drug candidates with unprecedented accuracy. Machine learning models predict compound efficacy and safety, accelerating earlystage drug development. AI also facilitates drug repurposing, uncovering new therapeutic uses for existing medications. At the drug delivery front, AI optimizes formulations and systems, enabling targeted and personalized approaches. Intelligent algorithms enhance the understanding of pharmacokinetics and pharmacodynamics, guiding the development of precision medicine strategies. This integration of AI not only expedites innovative drug discovery but also refines delivery mechanisms, promising more effective and tailored treatments with the potential to revolutionize patient care. The data-processing capabilities of AI drive digitalization and widespread utilization. Applications in drug discovery, development, repurposing, and clinical trials aim to alleviate human workload, expedite objectives, and foster innovation. Despite promising prospects, concerns about job displacement and stringent regulations accompany AI implementation. Emphasizing the intent to augment human labor rather than replace it entirely, the industry anticipates that AI will become a pivotal resource, propelling efficiency, innovation, and advancements in healthcare. This review emphasizes the role of AI in transforming drug discovery and delivery
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来源期刊
Current Drug Therapy
Current Drug Therapy PHARMACOLOGY & PHARMACY-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.
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