等离子体增强化学气相沉积法合成的铜涂层碳纳米管对大肠杆菌和金黄色葡萄球菌的抗菌活性

IF 1.3 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Main Group Chemistry Pub Date : 2024-07-12 DOI:10.3233/mgc-240020
Pouya Sepehr, S. M. Borghei, Morad Ebrahimkhas, Nasim Nobari
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引用次数: 0

摘要

随着抗生素耐药菌株的增加,有必要研制出不会诱发微生物耐药性的抗菌剂。本研究旨在评估等离子体增强化学气相沉积(PECVD)法合成的铜箔碳纳米管(Cu/CNTs)对两种革兰氏阳性菌(金黄色葡萄球菌)和革兰氏阴性菌(大肠杆菌)的抗菌效果。首先,利用电子束枪将碳纳米管(CNTs)沉积在之前用镍催化剂装饰过的高电阻率硅晶片上,然后将这些碳纳米管涂覆在高电阻率硅晶片上。然后在真空蒸发器中使用直流(DC)磁控溅射法在这些纳米管上镀上铜薄膜(Cu,0- 60 nm)。扫描电子显微镜(SEM)和透射电子显微镜(TEM)对 PECVD 生长的铜/CNT 的形态进行了研究。采用标准平板计数法(SPC)测定了合成的 Cu/CNTs 对大肠杆菌(E. coli)和金黄色葡萄球菌(S. aureus)的抗菌性能。结果表明,增加 Cu/CNTs 涂层厚度可增强其抗菌活性。SEM 和 TEM 图像证实了镀铜后样品的形态发生了改变。
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Antibacterial activity of copper-coated carbon nanotubes synthesized by plasma-enhanced chemical vapor deposition against Escherichia coli and Staphylococcus aureus
 The increase of antibiotic-resistant strains has necessitated the generation of antibacterial agents that do not induce microbial resistance. The present study was conducted to evaluate the antibacterial effect of copper-coated carbon nanotubes (Cu/CNTs) synthesized by plasma-enhanced chemical vapor deposition (PECVD) on two strains of gram positive (Staphylococcus aureus) and gram negative (Escherichia coli) bacteria. First, the PECVD method was used to deposit carbon nanotubes (CNTs) on high-resistivity silicon wafers previously decorated with nickel catalyst by an electron beam gun. These nanotubes were then coated with copper thin films (Cu, 0– 60 nm) in a vacuum evaporator using the Direct Current (DC) Magnetron Sputtering method. The morphology of PECVD-grown Cu/CNTs was investigated by scanning electron microscope (SEM) and transmission electron microscope (TEM). The antibacterial properties of as-synthesized Cu/CNTs against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were determined using Standard Plate Count (SPC). The results showed that increasing the coating thickness of Cu/CNTs had intensified their antibacterial activity. The SEM and TEM images confirmed the morphological modification of the samples after coating with copper.
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来源期刊
Main Group Chemistry
Main Group Chemistry 化学-化学综合
CiteScore
2.00
自引率
26.70%
发文量
65
审稿时长
>12 weeks
期刊介绍: Main Group Chemistry is intended to be a primary resource for all chemistry, engineering, biological, and materials researchers in both academia and in industry with an interest in the elements from the groups 1, 2, 12–18, lanthanides and actinides. The journal is committed to maintaining a high standard for its publications. This will be ensured by a rigorous peer-review process with most articles being reviewed by at least one editorial board member. Additionally, all manuscripts will be proofread and corrected by a dedicated copy editor located at the University of Kentucky.
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