美容医学中的自体血小板浓缩物。

IF 17.5 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Periodontology 2000 Pub Date : 2024-07-31 DOI:10.1111/prd.12582
Catherine Davies, Richard J Miron
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引用次数: 0

摘要

这篇叙述性综述总结了目前有关自体血小板浓缩物(APCs)在美容医学中应用的知识,旨在为临床医生提供可靠的临床实践信息。自体血小板浓缩物含有血小板,可释放各种生长因子,潜在应用于面部和皮肤治疗。本综述探讨了 APCs 在面部美容方面的几种应用,包括痤疮瘢痕、嫩肤、黄褐斑、白癜风、妊娠纹、眶周年轻化、口周年轻化、毛发再生以及 APC 凝胶的丰盈效果。我们对截至 2023 年 10 月的文献数据库(PubMed/MEDLINE)进行了系统性回顾,以确定有关 APCs 在面部年轻化和皮肤科方面的随机对照试验(RCT)的英文文献。共筛选出 96 篇文章,其中包括富血小板血浆 (PRP)、富含生长因子的血浆 (PRGF) 和富血小板纤维蛋白 (PRF) 的文章。本文提供了从综述中获得的临床建议。总之,在面部美容中使用 APCs 是一种前景广阔但相对较新的治疗方法。总体而言,大多数研究都集中在 PRP 的使用上,并取得了积极的成果。只有少数研究对 PRP 和 PRF 进行了比较,所有研究都显示使用 PRF 有更好的效果。现有的研究存在局限性,包括样本量小和缺乏标准化的评估标准。未来的研究应利用设计良好的 RCT,纳入适当的对照(如分面比较)和标准化的 APC 使用方案,包括最佳疗程次数、疗程间隔和客观改善评分。尽管如此,最新的血小板浓缩物配方还是为临床医生提供了改善各种临床参数和美学问题的能力。
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Autolougous platelet concentrates in esthetic medicine.

This narrative review summarizes current knowledge on the use of autologous platelet concentrates (APCs) in esthetic medicine, with the goal of providing clinicians with reliable information for clinical practice. APCs contain platelets that release various growth factors with potential applications in facial and dermatologic treatments. This review examines several facial esthetic applications of APCs, including acne scarring, skin rejuvenation, melasma, vitiligo, stretchmarks, peri-orbital rejuvenation, peri-oral rejuvenation, hair regeneration and the volumizing effects of APC gels. A systematic review of literature databases (PubMed/MEDLINE) was conducted up to October 2023 to identify randomized controlled trials (RCTs) in the English language on APCs for facial rejuvenation and dermatology. A total of 96 articles were selected including those on platelet rich plasma (PRP), plasma-rich in growth factors (PRGF), and platelet-rich fibrin (PRF). Clinical recommendations gained from the reviews are provided. In summary, the use of APCs in facial esthetics is a promising yet relatively recent treatment approach. Overall, the majority of studies have focused on the use of PRP with positive outcomes. Only few studies have compared PRP versus PRF with all demonstrating superior outcomes using PRF. The existing studies have limitations including small sample sizes and lack of standardized assessment criteria. Future research should utilize well-designed RCTs, incorporating appropriate controls, such as split-face comparisons, and standardized protocols for APC usage, including optimal number of sessions, interval between sessions, and objective improvement scores. Nevertheless, the most recent formulations of platelet concentrates offer clinicians an ability to improve various clinical parameters and esthetic concerns.

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来源期刊
Periodontology 2000
Periodontology 2000 医学-牙科与口腔外科
CiteScore
34.10
自引率
2.20%
发文量
62
审稿时长
>12 weeks
期刊介绍: Periodontology 2000 is a series of monographs designed for periodontists and general practitioners interested in periodontics. The editorial board selects significant topics and distinguished scientists and clinicians for each monograph. Serving as a valuable supplement to existing periodontal journals, three monographs are published annually, contributing specialized insights to the field.
期刊最新文献
Periodontal disease: A systemic condition. Periodontal diseases in Africa. Autogenous platelet concentrates for treatment of intrabony defects—A systematic review with meta‐analysis Orthodontic management of uneven gingival margins in patients with healthy or reduced periodontium to improve smile aesthetics. Autologous platelet concentrates in root coverage procedures.
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