H Poerwosusanta, Y A Saputra, A S Budi, D Aditia, Gunadi
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引用次数: 0
摘要
导言：赫氏普隆氏病相关性小肠结肠炎（HAEC）仍然是赫氏普隆氏病的一个重大发病和死亡风险。HAEC 是一项挑战。其病理生理学仍是一个谜，也没有适当的治疗策略。本研究旨在分析与 HAEC 相关的术前和术后、死亡率和并发症：狭窄、吻合口漏、便秘和失禁：根据《2020 年系统综述和荟萃分析首选报告项目》（PRISMA）进行调整；本研究符合所有要求，并且是最新的。检索方法为Pubmed和SagePub中2013年至2023年间的在线出版物。决定不考虑已经发表和完成一半的综述文章。使用 STATA 第 18 版进行荟萃分析：我们的搜索结果包括 370 篇 PubMed 和 149 篇 SagePub 文章。自 2013 年以来，共获得 134 篇 PubMed 和 9 篇 SagePub 文章，有 7 项研究符合标准：结论：激动段肠蠕动紊乱和粪便堆积破坏了微生物群的平衡，是导致术前 HAEC 的因素。重大先天性畸形和低出生体重会加重术前 HAEC。术前 HAEC 可持续并影响术后。便秘和大便失禁仍是 HSCR 手术后的主要难题。
Hirschsprung disease associated enterocolitis: a systematic review and meta-analysis.
Introduction: Hirschsprung's disease-associated enterocolitis (HAEC) remains a substantial morbidity and mortality risk in Hirschsprung's disease. HAEC is a challenge. Its p athophysiology is still a mystery, and no adequate treatment strategy exists. The aim of the study is to analyse the pre-and post-operative, mortality and complications: strictures, anastomotic leak, constipation and incontinence associated with HAEC.
Materials and methods: Adjust to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020; this study met all the requirements and was up-todate. The search approach was online publications between 2013 and 2023 in Pubmed and SagePub. It was decided not to consider review pieces that had already been published and half done. The STATA 18th version was used for metaanalysis.
Results: Our search results included 370 PubMed and 149 SagePub articles. Since 2013, 134 PubMed and nine SagePub articles have been obtained, and seven studies have met the criteria.
Conclusion: Disorders of intestinal motility in the aganglionic segment and accumulation of faeces disrupt the balanced microbiota population, which are factors of preoperative HAEC. Major congenital anomalies and low birth weight worsen pre-operative HAEC. Pre-operative HAEC can continue and affect the post-operative. Constipation and fecal incontinence are still the main challenges after HSCR surgery.
期刊介绍：
Published since 1890 this journal originated as the Journal of the Straits Medical Association. With the formation of the Malaysian Medical Association (MMA), the Journal became the official organ, supervised by an editorial board. Some of the early Hon. Editors were Mr. H.M. McGladdery (1960 - 1964), Dr. A.A. Sandosham (1965 - 1977), Prof. Paul C.Y. Chen (1977 - 1987). It is a scientific journal, published quarterly and can be found in medical libraries in many parts of the world. The Journal also enjoys the status of being listed in the Index Medicus, the internationally accepted reference index of medical journals. The editorial columns often reflect the Association''s views and attitudes towards medical problems in the country. The MJM aims to be a peer reviewed scientific journal of the highest quality. We want to ensure that whatever data is published is true and any opinion expressed important to medical science. We believe being Malaysian is our unique niche; our priority will be for scientific knowledge about diseases found in Malaysia and for the practice of medicine in Malaysia. The MJM will archive knowledge about the changing pattern of human diseases and our endeavours to overcome them. It will also document how medicine develops as a profession in the nation. We will communicate and co-operate with other scientific journals in Malaysia. We seek articles that are of educational value to doctors. We will consider all unsolicited articles submitted to the journal and will commission distinguished Malaysians to write relevant review articles. We want to help doctors make better decisions and be good at judging the value of scientific data. We want to help doctors write better, to be articulate and precise.
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