利用工程微生物系统监测和消除合成污染物

IF 1.9 4区 物理与天体物理 Q2 BIOLOGY Origins of Life and Evolution of Biospheres Pub Date : 2024-07-30 DOI:10.1007/s11084-024-09652-7
Quratulain Maqsood, Nazim Hussain, Aleena Sumrin, Shinawar Waseem Ali, Muhammad Rizwan Tariq, Muhammada Mahnoor
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引用次数: 0

摘要

合成污染物(SPs)在环境中的广泛使用和持久性使其成为一个重大的环境问题。为解决这一问题,人们探索了各种修复策略,包括光催化、纳米修复和生物修复。其中,生物修复是一种很有前景的方法,尤其是在使用基因工程(GE)微生物的情况下。本综述重点介绍 GE 微生物在减少环境系统中 SPs 方面的作用。GE 微生物经过改良,可增强其高效降解有机和无机 SPs 的能力。对负责污染物降解的关键基因进行了鉴定和改造,以提高分解率。此外,还讨论了使工程细菌更易被接受的策略。总之,基因工程微生物在污染物降解方面代表了一种可行且高效的本地菌株替代品,凸显了它们在应对环境污染挑战方面的潜力。
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Monitoring and abatement of synthetic pollutants using engineered microbial systems

Synthetic pollutants (SPs) are a significant environmental concern due to their extensive use and persistence in the environment. Various remediation strategies have been explored to address this issue, including photocatalysis, nano-remediation, and bioremediation. Among these, bioremediation stands out as a promising approach, particularly with the use of genetically engineered (GE) microorganisms. This review focuses on the role of GE microorganisms in reducing SPs from environmental systems. GE microorganisms have been modified to enhance their ability to degrade organic and inorganic SPs efficiently. Key genes responsible for contaminant degradation have been identified and modified to improve breakdown rates. Strategies to make engineered bacteria more acceptable are also discussed. Overall, GE microorganisms represent a viable and efficient alternative to native strains for pollutant degradation, highlighting their potential in addressing environmental pollution challenges.

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来源期刊
CiteScore
3.20
自引率
15.00%
发文量
12
审稿时长
>12 weeks
期刊介绍: The subject of the origin and early evolution of life is an inseparable part of the general discipline of Astrobiology. The journal Origins of Life and Evolution of Biospheres places special importance on the interconnection as well as the interdisciplinary nature of these fields, as is reflected in its subject coverage. While any scientific study which contributes to our understanding of the origins, evolution and distribution of life in the Universe is suitable for inclusion in the journal, some examples of important areas of interest are: prebiotic chemistry and the nature of Earth''s early environment, self-replicating and self-organizing systems, the theory of the RNA world and of other possible precursor systems, and the problem of the origin of the genetic code. Early evolution of life - as revealed by such techniques as the elucidation of biochemical pathways, molecular phylogeny, the study of Precambrian sediments and fossils and of major innovations in microbial evolution - forms a second focus. As a larger and more general context for these areas, Astrobiology refers to the origin and evolution of life in a cosmic setting, and includes interstellar chemistry, planetary atmospheres and habitable zones, the organic chemistry of comets, meteorites, asteroids and other small bodies, biological adaptation to extreme environments, life detection and related areas. Experimental papers, theoretical articles and authorative literature reviews are all appropriate forms for submission to the journal. In the coming years, Astrobiology will play an even greater role in defining the journal''s coverage and keeping Origins of Life and Evolution of Biospheres well-placed in this growing interdisciplinary field.
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