持续葡萄糖监测及其葡萄糖计量学在西班牙临床实践中的影响和未来展望:叙述性综述。

IF 3.4 3区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL Advances in Therapy Pub Date : 2024-08-02 DOI:10.1007/s12325-024-02943-5
Fernando Gómez-Peralta, Isabel Leiva-Gea, Natalia Duque, Esther Artime, Miriam Rubio de Santos
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引用次数: 0

摘要

简介连续血糖监测(CGM)设备可 24 小时实时测量血糖水平,改变了糖尿病患者与医疗服务提供者之间的互动。CGM 生成的大量数据可通过一组标准化参数(统称为葡萄糖计量学)进行分析和评估。本综述旨在根据已发表的涉及西班牙 1 型糖尿病(T1D)成人和儿童患者的研究,总结葡萄糖计量学数据使用的现有证据及其对临床实践的影响:在PubMed和MEDES(西班牙医学文献)数据库中检索了2018-2022年期间在西班牙进行的有关CGM和血糖测量的临床和观察性研究、共识指南和荟萃分析:共找到 16 项关于 CGM 在西班牙使用情况的观察性研究,这些研究表明,在引入 CGM 后,T1D 儿童严重低血糖的病例大大减少,从而显著降低了成本。西班牙的实际数据显示,CGM 与血糖指标的改善有关(在血糖范围内的时间增加,低于和高于血糖范围的时间减少,以及血糖变异性),而血糖变异性与低血糖之间存在关系。此外,在 COVID-19 大流行期间,CGM 和血糖测量分析证明非常有用。新的血糖测量方法,如血糖风险指数,或分析 CGM 导出血糖数据的新数学方法,如 "血糖密度",可帮助患者在未来更好地控制血糖:通过在临床实践中使用血糖计量学,临床医生可以更好地评估血糖控制情况和患者对治疗的个体反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Impact of Continuous Glucose Monitoring and its Glucometrics in Clinical Practice in Spain and Future Perspectives: A Narrative Review

Introduction

Continuous glucose monitoring (CGM) devices allow for 24-h real-time measurement of interstitial glucose levels and have changed the interaction between people with diabetes and their health care providers. The large amount of data generated by CGM can be analyzed and evaluated using a set of standardized parameters, collectively named glucometrics. This review aims to provide a summary of the existing evidence on the use of glucometrics data and its impact on clinical practice based on published studies involving adults and children with type 1 diabetes (T1D) in Spain.

Methods

The PubMed and MEDES (Spanish Medical literature) databases were searched covering the years 2018–2022 and including clinical and observational studies, consensus guidelines, and meta-analyses on CGM and glucometrics conducted in Spain.

Results

A total of 16 observational studies were found on the use of CGM in Spain, which have shown that cases of severe hypoglycemia in children with T1D were greatly reduced after the introduction of CGM, resulting in a significant reduction in costs. Real-world data from Spain shows that CGM is associated with improved glycemic markers (increased time in range, reduced time below and above range, and glycemic variability), and that there is a relationship between glycemic variability and hypoglycemia. Also, CGM and analysis of glucometrics proved highly useful during the COVID-19 pandemic. New glucometrics, such as the glycemic risk index, or new mathematical approaches to the analysis of CGM-derived glucose data, such as “glucodensities,” could help patients to achieve better glycemic control in the future.

Conclusion

By using glucometrics in clinical practice, clinicians can better assess glycemic control and a patient's individual response to treatment.

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来源期刊
Advances in Therapy
Advances in Therapy 医学-药学
CiteScore
7.20
自引率
2.60%
发文量
353
审稿时长
6-12 weeks
期刊介绍: Advances in Therapy is an international, peer reviewed, rapid-publication (peer review in 2 weeks, published 3–4 weeks from acceptance) journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of therapeutics and interventions (including devices) across all therapeutic areas. Studies relating to diagnostics and diagnosis, pharmacoeconomics, public health, epidemiology, quality of life, and patient care, management, and education are also encouraged. The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Advances in Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.
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