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引用次数: 0
摘要
新形成的人类 B 细胞作为过渡性细胞从骨髓中出现后不久，就会沿着两条发育途径分化，这两条途径可根据其表达的 IgM 水平和迁移偏向加以区分。在这里，我们提出未成熟 B 细胞亚群的不同组织归巢有助于人类淋巴组织的结构和功能。
Immature B cell homing shapes human lymphoid tissue structure and function.
Shortly after the emergence of newly formed human B cells from bone marrow as transitional cells, they diverge along two developmental pathways that can be distinguished by the level of IgM they express and migratory biases. Here, we propose that differential tissue homing of immature B cell subsets contributes to human lymphoid tissue structure and function.
期刊介绍：
Since its establishment in 1896, the Journal of Experimental Medicine (JEM) has steadfastly pursued the publication of enduring and exceptional studies in medical biology. In an era where numerous publishing groups are introducing specialized journals, we recognize the importance of offering a distinguished platform for studies that seamlessly integrate various disciplines within the pathogenesis field.
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